A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(L-Lactide-Co-Caprolactone) for Endothelial Cells Delivery and Skin Wound Repair
December 2018
in “
ACS Biomaterials Science & Engineering
”
fibrous hybrid patch human fibroblast-derived extracellular matrix poly(L-lactide-co-caprolactone) skin wound repair endothelial cell delivery human umbilical vein endothelial cells vascular morphogenesis human dermal fibroblasts wound healing hair follicle reappearance neovascularization cell-matrix interactions tissue engineering regenerative medicine hFDM PLCL HUVECs hDFB
Studysummary This research found that a biodegradable fibrous membrane incorporating fibroblast-derived ECM accelerated wound healing and improved neovascularization in a mouse model.
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