TLDR Leucocyte-rich platelet-rich plasma boosts cell activity and helps wound healing.
The study investigated the effects of leucocyte-rich platelet-rich plasma (LR-PRP) on human fibroblasts compared to leucocyte-poor, platelet-poor plasma (LP-PPP). LR-PRP, with significantly higher concentrations of platelets and white blood cells, enhanced fibroblast cell proliferation and migration. It also influenced the gene expression of extracellular matrix and adhesion molecules, showing either upregulation or down-regulation. The findings suggested that LR-PRP had a continuous stimulatory anabolic and ergogenic effect on human fibroblast cells, indicating its potential benefits in wound healing.
71 citations
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December 2018 in “Journal of Pain Research”
29 citations
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January 2018 in “International Journal of Trichology” PRP treatment helps hair growth and density with 70.7% success, but more research needed.
56 citations
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November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
57 citations
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May 2016 in “Journal of Dermatological Treatment” PRP therapy may effectively treat hair loss, but more research needed.
12 citations
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April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
67 citations
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May 2014 in “International Journal of Molecular Sciences” Using your own skin cells can help repair aging skin and promote hair growth.
56 citations
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November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
348 citations
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July 2017 in “Skin appendage disorders” Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
1 citations
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June 2018 in “Advances in Cosmetic Surgery” PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.
7 citations
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December 2018 in “Discoveries” Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
12 citations
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March 2018 in “Bioengineering” The document concludes that products like PRP and PRF show promise for tissue healing, but evidence of their effectiveness is inconsistent.