TLDR Leucocyte-rich platelet-rich plasma boosts cell activity and helps wound healing.
The study investigated the effects of leucocyte-rich platelet-rich plasma (LR-PRP) on fibroblast activity and extracellular matrix dynamics, which are crucial for wound healing. It found that LR-PRP significantly enhanced fibroblast proliferation and migration, achieving 100% wound closure in 48 hours compared to 60.1% with leucocyte-poor platelet-poor plasma (LP-PPP). The research highlighted the upregulation of genes involved in extracellular matrix remodeling and cell adhesion, suggesting LR-PRP's potential as a complementary treatment for delayed wound healing. However, the study was conducted in vitro and not directly applicable to clinical settings.
71 citations
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December 2018 in “Journal of Pain Research” Standardizing PRP preparation and application could improve its effectiveness for chronic pain relief.
29 citations
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January 2018 in “International Journal of Trichology” PRP treatment helps hair growth and density with 70.7% success, but more research needed.
56 citations
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November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
57 citations
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May 2016 in “Journal of Dermatological Treatment” PRP therapy may effectively treat hair loss, but more research needed.
12 citations
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April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
67 citations
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May 2014 in “International Journal of Molecular Sciences” Using your own skin cells can help repair aging skin and promote hair growth.
56 citations
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November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
348 citations
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July 2017 in “Skin appendage disorders” Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
1 citations
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June 2018 in “Advances in Cosmetic Surgery” PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.
848 citations
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October 2020 in “International Journal of Molecular Sciences” PRP shows promise in treating joint and spine issues, but translating lab results to humans is challenging.
7 citations
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December 2018 in “Discoveries” Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
