Biotherapeutic Applications of Platelet-Rich Plasma in Regenerative Medicine
August 2023
in “
Tissue Engineering and Regenerative Medicine
”
Research cited in this study
27 / 27 resultsresearch A Comparative Study of Efficacy of 5% Minoxidil and 5% Minoxidil Plus Platelet-Rich Plasma in the Same Patient for Treatment of Androgenetic Alopecia
This study found that adding platelet-rich plasma to 5% minoxidil treatment improved hair growth outcomes in patients with androgenetic alopecia compared to minoxidil alone.
research Minoxidil: A Comprehensive Review
This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.
research Systematic Review of Platelet-Rich Plasma in Treating Alopecia: Focusing on Efficacy, Safety, and Therapeutic Durability
This review found that platelet-rich plasma therapy improved hair growth and thickness in most studies on alopecia, with the highest improvement seen when combined with Minoxidil.
research Technical Procedures for Preparation and Administration of Platelet-Rich Plasma and Related Products: A Scoping Review
This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.
research Leucocyte-Rich Platelet-Rich Plasma Enhances Fibroblast and Extracellular Matrix Activity: Implications in Wound Healing
This study concluded that leucocyte-rich PRP has a continuous stimulatory effect on human fibroblast cells, enhancing their proliferation, migration, and impacting gene expression of the extracellular matrix and adhesion molecules.
research Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia
This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.
research The Effect of Platelet-Rich Plasma on Female Androgenetic Alopecia: A Randomized Controlled Trial
This study found that PRP injections using the Eclipse system significantly improved hair density and caliber in women with androgenetic alopecia compared to saline placebo at 24 weeks.
research Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety
This study concluded that oral minoxidil is an effective and well-tolerated alternative to topical minoxidil for healthy patients struggling with application-related compliance issues.
research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy
This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.
research Platelet-Rich Plasma and Regenerative Dentistry
This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.
research Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo
This study found that the combination of epidermal growth factor and Jagged1 significantly stimulated hair growth in mice with androgen-suppressed conditions, suggesting potential therapeutic implications for androgenetic alopecia.
research Comparison of Efficacy of Platelet-Rich Plasma Therapy With or Without Topical 5% Minoxidil in Male-Type Baldness: A Randomized, Double-Blind Placebo Control Trial
This study found that platelet-rich plasma combined with topical minoxidil was more effective in increasing hair density for male-type baldness than either treatment alone.
research The Effect of Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia
This study found that platelet-rich plasma may effectively increase hair follicle numbers in men with androgenetic alopecia, but changes in hair thickness plateaued after the second injection.
research Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia Patients
In this study, patients with androgenetic alopecia treated with platelet-rich plasma showed increased hair density and improved hair quality over six months, with no notable adverse effects, indicating that PRP may be an effective treatment option for this condition.
research Alopecia Areata: Overview and Insights from January 2018
This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.
research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification
This review discusses the use of platelet-rich plasma in dermatology for various applications such as tissue regeneration and wound healing, but it reports no new clinical results and calls for clearer guidance on suitable treatments.
research Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study
Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.
research Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal
This study found that platelet-derived growth factor signaling is crucial for maintaining the hair follicle dermal stem cell pool and supporting their regenerative capacity.
research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia
This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.
research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial
This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.
research Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice
In this study, topical application of fibroblast growth factors was found to promote hair growth by inducing and prolonging the anagen phase in telogenic C57BL/6 mice, suggesting potential as hair growth-promoting agents.
research Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia
This study found that platelet-rich plasma injections led to improvements in hair counts, thickness, and strength in patients with androgenic alopecia, showing promise as an effective treatment with no major adverse effects.
research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition
This study found that JAK inhibitors promote hair regrowth in both mice and human alopecia areata cases by blocking key immune pathways involved in disease development.
research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia
This review discusses current therapeutic targets and treatments for androgenic alopecia but reports no clinical results; the authors highlight the challenge of developing multi-target drugs for effective treatment.
research Hematological And Hepatic Effects Of Vascular Epidermal Growth Factor (VEGF) Used To Stimulate Hair Growth In An Animal Model
In this animal study, topical VEGF gel increased hair growth and thickness in Mesocricetus auratus, although it was not completely inert, highlighting the need for further toxicity confirmation.
research Cause of Androgenic Alopecia
This review examines misconceptions and gaps in the understanding of androgenic alopecia (AGA) etiopathogenesis, offering new perspectives but no new experimental results.
research Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B
In this study, IGF-I was shown to enhance human hair follicle growth, maintain the anagen phase, and increase expression of certain growth factors and anti-apoptotic markers.
Related Research
1 / 1 results
research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia
In this study, researchers found that homologous PRP (h-PRP) significantly increased hair density more than both nonactivated (n-PRP) and activated (a-PRP) autologous PRP in patients with androgenetic alopecia, suggesting h-PRP as a potentially more effective treatment option for hair loss.