Extracellular Vesicles for Cosmetic Applications

    May 2023
    Apolonija Bedina Zavec
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    TLDR Tiny particles called extracellular vesicles show potential for improving skin health in cosmetics, but more research is needed to confirm their safety and effectiveness.
    Extracellular vesicles (EVs) are highlighted as promising active ingredients for cosmetic applications due to their delivery capacity and ability to influence recipient cells. The review covers EVs from various sources including mesenchymal stem cells (MSCs), platelets, skin microbiota, and microalgae. MSC-derived EVs have shown potential for antiaging and wound healing but are not yet approved for use in cosmetics or medicine in Europe and the US. Platelet-rich plasma containing EVs has been well received for facial rejuvenation through injections and topical applications. EVs from skin-friendly microbes are already incorporated into cosmetic products, and microalgae-derived EVs are noted for their antioxidant properties. The review concludes that EVs hold significant promise for skin health and condition improvement, but further research is necessary to establish their safety and effectiveness in cosmetics.
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