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This study found that GLI2 plays a key role in activating follistatin, an activin/BMP antagonist, in response to hedgehog signaling in human epidermal cells, with implications for hair follicle development and basal cell carcinoma.

This study reported that introducing the TERT and Bmi1 genes into mouse dermal papilla cells resulted in immortal cells capable of inducing new hair follicles in vivo, and human immortal DPCs were also developed.

This study found that valproic acid and crocin, alone or together, significantly increased the expression levels of neurotrophic factors in rat-derived epidermal neural crest stem cells, suggesting therapeutic potential for neurological disorders.

This study observed that the isotope-dilution GC-MS technique can assess 5α-reductase activity more effectively than conventional methods in rat liver S9 fractions, particularly at low testosterone levels.

This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.

This study found that daily injections of basic and acidic fibroblast growth factor in newborn mice significantly delayed hair follicle development within the treatment area, while epidermal growth factor affected the entire body coat and caused skin hyperkeratinization.

This study found that Crataegi Fructus water extract may promote hair growth in mice by enhancing hair density, thickness, and length and activating the Wnt/β-catenin signaling pathway.

Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.

This study found that the fuzzy mutation in mice is linked to both structural hair defects and accelerated hair follicle cycling, influencing the regulation of hair cycle phases such as catagen and anagen.

In this study, cosyntropin-induced cortisol spikes did not affect hair cortisol concentration in captive grizzly bears, contrasting with stress responses observed in free-ranging bears during capture.

This study found that KF19418 stimulated hair follicle growth in vitro and accelerated hair regrowth in a mouse alopecia model, with effects comparable to minoxidil.

This study developed a rapid and efficient in vitro method using high-performance liquid chromatography to screen for steroid 5 alpha-reductase inhibitors, determining inhibition constants for Finasteride and Epristeride.

In a laboratory study, researchers found that a novel Bioactive Crosslink Repair Complex improved both the protection and repair of chemically damaged hair, enhancing tensile strength, shine, and cuticle alignment when added to bleaching mixtures and leave-in conditioners.

In this study, researchers demonstrated that their technology efficiently produces CFx-δ2 from stem cells and accelerates wound healing by enhancing fibroblast activity, reducing inflammation, and promoting blood vessel formation.

This study explored the potential of human hair keratin as a filtration material, finding that it may effectively absorb the pollutants diclofenac and perfluorobutanesulfonate. The researchers reported significant binding affinities through molecular simulations, supporting further investigation into keratin's use for water purification.

This study developed a method to culture and maintain chicken feather follicles in vitro, preserving structure and biology similar to their in vivo state, though some gene expression was altered.

CaBP1 and 2 are important for maintaining the activity of calcium channels necessary for hearing in inner ear cells.

In this study using diabetic rat models, the combination of AMD3100 and low-dose FK506 reduced wound healing time and improved microcirculation in diabetic foot ulcers, indicating a promising new systemic therapy.

The researchers reported that glucuronides stored as dried blood spots under ambient conditions exhibited stability equivalent to liquid samples stored at -80°C.

In this animal study, serum biotin levels and clinical symptoms in gilts suggested that serum biotin could serve as a sensitive indicator of biotin deficiency, and a system to evaluate biotin status was proposed.

This research describes using advanced mass spectrometry imaging techniques to analyze gunshot residue and map molecular components in biological samples, such as tumors and mosquito ovarian follicles, at unprecedented spatial resolution and specificity.

Brepocitinib improves cicatricial alopecia and reduces key immune markers.

This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.

This study introduced a new computational method for simulating vibrational frequencies, finding that the multi-molecular fragment model showed the best agreement with experimental data for Finasteride, Lamivudine, and Repaglinide, outperforming traditional models in accuracy.

This study observed that chemically-induced intersex frogs displayed altered brain mRNA profiles, with finasteride increasing certain hormone-related gene expressions and fadrozole reducing aromatase activity without affecting gene transcript levels.

This article reviews cell proteomic footprinting technology and its application in improving the authentication and quality control of cell-based immunotherapeutics, without providing new clinical results.

This study found that Y27632 treatment facilitated the formation of core-shell-shaped hair follicle organoids, resulting in nearly 100% efficient hair shaft sprouting in vitro.

Mutations in Far2 mice cause hair loss due to sebaceous gland issues.

This protocol describes a method for cultivating stem cells on a fibrin carrier for potential transplantation to the eye, but it reports no new clinical findings.