Murine Hair Follicle Derived Stem Cell Transplantation onto the Cornea Using a Fibrin Carrier
January 2018
in “
BIO-PROTOCOL
”
TLDR Hair follicle stem cells can be transplanted onto the eye using a fibrin carrier to help repair eye damage.
The study explored the transplantation of hair follicle-derived stem cells onto the cornea of limbal stem cell-deficient mice using fibrin carriers. The fibrin gel supported cell attachment, migration, and proliferation. Over 5 weeks, fluorescent microscopy showed that the transplanted stem cells successfully integrated and differentiated into corneal epithelial cells. This suggested potential therapeutic applications for treating limbal stem cell deficiency.
