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GlossaryCorneal Epithelium

outermost cell layer of the eye's clear front surface

The corneal epithelium is the outermost layer of the cornea, which is the clear, dome-shaped surface that covers the front of the eye. This thin, protective layer of cells helps to shield the eye from dust, debris, and bacteria, while also playing a crucial role in maintaining clear vision by providing a smooth surface for light to enter the eye.

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Network Analysis Reveals Potential Mechanisms That Determine the Cellular Identity of Keratinocytes and Corneal Epithelial Cells Through the Hox/Gtl2-Dio3 miRNA Axis

research Network Analysis Reveals Potential Mechanisms That Determine the Cellular Identity of Keratinocytes and Corneal Epithelial Cells Through the Hox/Gtl2-Dio3 miRNA Axis

January 2025 in “Frontiers in Cell and Developmental Biology”

Hox proteins help maintain keratinocyte identity by regulating miRNA expression.

research Epithelial-Mesenchymal Interactions Promote Hair Follicle Neogenesis and a New Stem Cell Niche in Adult Corneal Epithelium

August 2009 in “Mechanisms of Development”

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

research Keratin Expression by Corneal and Limbal Stem Cells During Development

25 citations, November 2020 in “Experimental eye research/Experimental Eye Research”

Different types of cells in the eye express specific keratins at various stages of development.

research Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling

15 citations, August 2020 in “American Journal of Pathology”

Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.

research Epithelial Stem Cells: Turning Over New Leaves

508 citations, February 2007 in “Cell”

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 828 upvotes 5 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community 1 Year Update: 1mg Dutasteride daily and 2.5-5mg oral Minoxidil Daily on Diffuse Unpatterned Alopecia

in Progress Pictures 1409 upvotes 9 months ago

A user shared a 1-year update showing hair regrowth from taking 1mg Dutasteride and 2.5-5mg oral Minoxidil daily for Diffuse Unpatterned Alopecia. Some comments praised the results, while others criticized the user's behavior and questioned potential side effects.

community 8 mos: oral (Du, Min), topical (Min, Ru, Ketoconazole), microneedling. NW7 for 7 years

in Progress Pictures 942 upvotes 2 years ago

A user's success in hair regrowth after taking oral and topical medications, such as minoxidil and dutasteride, and using microneedling. Other users shared their experiences and advice with treatments used to reverse hair loss.

community 3 and a half months on Fin MWF, min daily and microneedling once a week.

in Progress Pictures 685 upvotes 2 years ago

A user's progress with treating hair loss over 3.5 months, which involves taking finasteride MWF, minoxidil daily and microneedling once a week. There was positive feedback from other users regarding the results.

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