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    Glossary Corneal Epithelium

    outermost cell layer of the eye's clear front surface

    The corneal epithelium is the outermost layer of the cornea, which is the clear, dome-shaped surface that covers the front of the eye. This thin, protective layer of cells helps to shield the eye from dust, debris, and bacteria, while also playing a crucial role in maintaining clear vision by providing a smooth surface for light to enter the eye.

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    1. Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells Stem Cells · 2008 · 162 citations
    2. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals Proceedings of the National Academy of Sciences · 2005 · 130 citations
    3. Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. The International Journal of Developmental Biology · 2004 · 55 citations
    4. 1378 Identification of two distinct stem cell clusters, Lrig1-derived and Wnt/CD44-dependent, in corneal epithelium Journal of Investigative Dermatology · 2018
    5. 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium Mechanisms of Development · 2009
    6. Network analysis reveals potential mechanisms that determine the cellular identity of keratinocytes and corneal epithelial cells through the Hox/Gtl2-Dio3 miRNA axis Frontiers in Cell and Developmental Biology · 2025
    7. Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1 Cell Biology International · 2009 · 20 citations
    8. Limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial‐like cells Acta Ophthalmologica · 2008
    9. Homeostatic maintenance of the murine corneal epithelium in pathophysiological contexts Työväentutkimus Vuosikirja · 2020
    10. Wnt7a can up-regulates cell adhesion related protein fibronectin expression and promotes cell proliferation in corneal epithelial cells 2023
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