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GlossaryCorneal Epithelium

outermost cell layer of the eye's clear front surface

The corneal epithelium is the outermost layer of the cornea, which is the clear, dome-shaped surface that covers the front of the eye. This thin, protective layer of cells helps to shield the eye from dust, debris, and bacteria, while also playing a crucial role in maintaining clear vision by providing a smooth surface for light to enter the eye.

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research Identification of Two Distinct Stem Cell Clusters, Lrig1-Derived and Wnt/CD44-Dependent, in Corneal Epithelium

April 2018 in “Journal of Investigative Dermatology”

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

research Epithelial-Mesenchymal Interactions Promote Hair Follicle Neogenesis and a New Stem Cell Niche in Adult Corneal Epithelium

August 2009 in “Mechanisms of Development”

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease

2 citations, September 2023 in “Curēus”

Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.

research Decoding Frontal Fibrosing Alopecia and Lichen Planopilaris: Macrophages Hold the Key?

April 2018 in “Journal of Investigative Dermatology”

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

research Cell of Origin Contributes to Melanoma Diversity

April 2018 in “Journal of Investigative Dermatology”

Different types of stem cells in the skin contribute to the variety of melanoma forms.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 1 month ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community 1 Year Update: 1mg Dutasteride daily and 2.5-5mg oral Minoxidil Daily on Diffuse Unpatterned Alopecia

in Progress Pictures 1404 upvotes 5 months ago

A user shared a 1-year update showing hair regrowth from taking 1mg Dutasteride and 2.5-5mg oral Minoxidil daily for Diffuse Unpatterned Alopecia. Some comments praised the results, while others criticized the user's behavior and questioned potential side effects.

community 8 mos: oral (Du, Min), topical (Min, Ru, Ketoconazole), microneedling. NW7 for 7 years

in Progress Pictures 941 upvotes 1 year ago

A user's success in hair regrowth after taking oral and topical medications, such as minoxidil and dutasteride, and using microneedling. Other users shared their experiences and advice with treatments used to reverse hair loss.

community 3 and a half months on Fin MWF, min daily and microneedling once a week.

in Progress Pictures 687 upvotes 1 year ago

A user's progress with treating hair loss over 3.5 months, which involves taking finasteride MWF, minoxidil daily and microneedling once a week. There was positive feedback from other users regarding the results.

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