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GlossaryCorneal Epithelium

outermost cell layer of the eye's clear front surface

The corneal epithelium is the outermost layer of the cornea, which is the clear, dome-shaped surface that covers the front of the eye. This thin, protective layer of cells helps to shield the eye from dust, debris, and bacteria, while also playing a crucial role in maintaining clear vision by providing a smooth surface for light to enter the eye.

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research Identification of Two Distinct Stem Cell Clusters, Lrig1-Derived and Wnt/CD44-Dependent, in Corneal Epithelium

April 2018 in “Journal of Investigative Dermatology”

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

research Epithelial-Mesenchymal Interactions Promote Hair Follicle Neogenesis and a New Stem Cell Niche in Adult Corneal Epithelium

August 2009 in “Mechanisms of Development”

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

research Thymosin β4 Promotes the Wound Healing of Cornea

January 2010

Thymosin β4 helps heal corneal wounds.

research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease

2 citations , September 2023 in “Curēus”

Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.

research Decoding Frontal Fibrosing Alopecia and Lichen Planopilaris: Macrophages Hold the Key?

April 2018 in “Journal of Investigative Dermatology”

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Finasteride and Eye Problems: You’re Not Going Crazy

in Finasteride/Dutasteride 503 upvotes 4 months ago

Finasteride can cause dry eyes and vision issues due to its impact on the meibomian glands. Users have mixed experiences, with some experiencing eye discomfort and others having no side effects.

community Blaming Finasteride doesn't help you solve anything: dry eyes

in Finasteride/Dutasteride 51 upvotes 6 months ago

Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 2 years ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community 1 Year Update: 1mg Dutasteride daily and 2.5-5mg oral Minoxidil Daily on Diffuse Unpatterned Alopecia

in Progress Pictures 1409 upvotes 1 year ago

A user shared a 1-year update showing hair regrowth from taking 1mg Dutasteride and 2.5-5mg oral Minoxidil daily for Diffuse Unpatterned Alopecia. Some comments praised the results, while others criticized the user's behavior and questioned potential side effects.

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