Identification of a Cyclosporine-Specific P450 Hydroxylase Gene Through Targeted Cytochrome P450 Complement Disruption in Sebekia Benihana

    Mi-Jin Lee, Hyun-Bum Kim, Yeo Joon Yoon … Eung-Soo Kim
    Studysummary This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.
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    Research cited in this study 1

    1. Topical Application of Cyclosporin A Induces Rapid Remodeling of Damaged Anagen Hair Follicles in Cyclophosphamide-Administered Mice Journal of Dermatological Science · 2001