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    Glossary Cytochrome P450

    enzymes metabolize drugs and toxins in the liver

    Cytochrome P450 (CYP) refers to a large family of enzymes that play a crucial role in the metabolism of various substances within the body, including drugs, toxins, and hormones. These enzymes are primarily found in the liver and are essential for the detoxification process, as well as the synthesis of cholesterol, steroids, and other lipids.

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    Research 10 of 1000+

    1. Testosterone, cytochrome P450, and cardiac hypertrophy The FASEB Journal · 2002 · 155 citations
    2. Cytochrome P450: A Target for Drug Development for Skin Diseases 2004 · 115 citations
    3. Comparison of Activities Dependent on Glutathione S-Transferase and Cytochrome P-450 IA1 in Cultured Keratinocytes and Reconstructed Epidermal Models Skin Pharmacology and Physiology · 2002 · 42 citations
    4. Immunohistochemical detection of cytochrome P450 isoenzymes in cultured human epidermal cells. Journal of Histochemistry & Cytochemistry · 1990 · 19 citations
    5. Identification of a Cyclosporine-Specific P450 Hydroxylase Gene through Targeted Cytochrome P450 Complement (CYPome) Disruption in Sebekia benihana Applied and Environmental Microbiology · 2013 · 13 citations
    6. Transcriptome sequencing and identification of cytochrome P450 monooxygenases involved in the biosynthesis of maslinic acid and corosolic acid in <i>Avicennia marina</i> Plant Biotechnology · 2018 · 10 citations
    7. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 7 citations
    8. Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1 Frontiers in Pharmacology · 2022 · 1 citations
    9. Identification of Potential Cytochrome p450c 17 Alpha Inhibitors for the Treatment of PCOS via Scaffold Hopping and Fragment-Based De-Novo Drug Design 2024
    10. The Role of Cytochrome P-450 in Dermatology International Journal of Dermatology · 1989 · 8 citations
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    Community 4

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    4. Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight? Reddit · 22 May 2024

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