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Identification of a Cyclosporine-Specific P450 Hydroxylase Gene Through Targeted Cytochrome P450 Complement Disruption in Sebekia Benihana

research Identification of a Cyclosporine-Specific P450 Hydroxylase Gene Through Targeted Cytochrome P450 Complement Disruption in Sebekia Benihana

13 citations , January 2013 in “Applied and Environmental Microbiology”

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

research Targets to Treat Androgen Excess in Polycystic Ovary Syndrome

14 citations , September 2015 in “Expert Opinion on Therapeutic Targets”

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

research Generating Disulfides in Multicellular Organisms: Emerging Roles for a New Flavoprotein Family

75 citations , March 2007 in “Journal of Biological Chemistry”

QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.

research Iron-Mediated DAMO-Anammox Process: Revealing the Mechanism of Electron Transfer

April 2024 in “Journal of environmental management”

Iron improves the DAMO-anammox process for treating water but too much iron can hinder it.

research Two-Ligand Priming Mechanism for Potentiated Phosphoinositide Synthesis Is an Evolutionarily Conserved Feature of Sec14-Like Phosphatidylinositol and Phosphatidylcholine Exchange Proteins

25 citations , May 2016 in “Molecular biology of the cell”

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

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Community Join

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community Should I dedicate my university studies to solving hair loss?

in Research/Science 373 upvotes 2 years ago

A 20 year old male who is balding and considering switching to a biology/chemistry program in order to find a low-cost, accessible solution for hair loss. Replies discuss the merits of this idea as well as potential treatments such as Minoxidil, finasteride, RU58841, TM5614, and ADQ.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

in Transgender 2256 upvotes 4 months ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

community The mechanism of androgenic alopecia

in Research/Science 33 upvotes 1 month ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community Possible natural pp405 solution

in Research/Science 45 upvotes 2 months ago

Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 1 year ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

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