Protective And Restorative Effects Of A Bio-Based Crosslinking Complex On Chemically Damaged Hair

December 2025 in “ Cosmetics ”

Flavio B. Camargo, Alessandra Mari Goshiyama, Gessica F. D. Oliveira, Marcos Roberto Rossan, Cleverson Princival, Edson Katekawa, Wagner Vidal Magalhães, Rafaela de Almeida Zito, Letícia Kakuda, Patrícia Maria Berardo Gonçalves Maia Campos

bioactive crosslink repair complex itaconic acid arginine D-panthenol polysaccharides linseed chia bleaching mixture leave-in conditioner tensile strength cuticle alignment denaturation vitamin B5 flaxseed chia seed

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Studysummary In a laboratory study, researchers found that a novel Bioactive Crosslink Repair Complex improved both the protection and repair of chemically damaged hair, enhancing tensile strength, shine, and cuticle alignment when added to bleaching mixtures and leave-in conditioners.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study evaluates a Bio-Based Crosslinking Complex (BCRC) composed of itaconic acid, arginine, D-panthenol, and polysaccharides from linseed and chia, designed to protect and repair chemically damaged hair, particularly from bleaching. BCRC was tested as both a protective agent in bleaching mixtures and a repair treatment in leave-in conditioners. Results from tests on 50 samples showed significant improvements in mechanical strength, thermal stability, shine, and combability of treated hair compared to untreated hair. BCRC-treated hair exhibited a 19.58% increase in tensile strength, restoring up to 92% of the original strength of virgin hair. These findings suggest BCRC's dual functionality as a promising protective and restorative agent for chemically treated hair.

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