Structural Investigation on Damaged Hair Keratin Treated with α,β-Unsaturated Michael Acceptors Used as Repairing Agents

December 2020 in “ International journal of biological macromolecules ”

Michele Di Foggia, Carla Boga, Gabriele Micheletti, Benedetta Nocentini, Paola Taddei

keratin bleached hair shikimic acid dimethyl maleate vibrational spectroscopy scanning electron microscopy cortex cuticle hair fibers commercial reconstructive agents

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Keratin →

Hair Fibers →

cosmetic product that temporarily makes hair appear thicker

Studysummary This study found that shikimic acid- and maleate-based hair repair agents modified the structure of hair fibers, though they did not increase disulfide bridge content in the hair cortex.

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The study investigated the structural changes in keratin from bleached hair treated with commercial reconstructive agents, shikimic acid, and dimethyl maleate using vibrational spectroscopy and scanning electron microscopy. Results showed that these agents interacted with both the cortex and cuticle regions of hair fibers, with more significant modifications observed in hair bleached three times compared to four times. Commercial agents were more effective than the model compounds in modifying hair fibers at the molecular level.

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