Arginine
Research
20 / 1000+ resultsresearch The Localization And Significance Of Arginine And Citrulline In Proteins Of The Hair Follicle
In this study, researchers localized arginine and citrulline in rat hair follicles and found that arginine is abundant in trichohyalin droplets, while citrulline predominantly accumulates in the hardened inner sheath and medulla.
research The Enzymic Derivation of Citrulline Residues from Arginine Residues In Situ During the Biosynthesis of Hair Proteins Cross-Linked by Isopeptide Bonds
Hair follicles have an enzyme that converts arginine to citrulline in proteins.
research Trichorrhexis Nodosa Secondary to Argininosuccinicaciduria
This report describes a 3.5-year-old girl with argininosuccinicaciduria, highlighting congenital trichorrhexis nodosa as a notable feature associated with the disorder.
research Histological Evaluation of Follicular Delivery of Arginine via Nanostructured Lipid Carriers: A Novel Potential Approach for the Treatment of Alopecia
This study found that arginine-loaded lipidic nanoparticles improved hair follicle growth in male hamsters more effectively than an aqueous arginine solution.
research Dietary Management Reverses Grooving And Abnormal Polarization Of Hair Shafts In Argininosuccinase Deficiency
This study observed that a low-protein, arginine-supplemented diet improved the abnormal hair appearance in untreated patients with argininosuccinic aciduria.
research Arginine Transferase Activity in Homogenates from Guinea Pig Hair Follicles
research Love Is in the Hair: Arginine Methylation of Human Hair Proteins as Novel Cardiovascular Biomarkers
This study found that protein arginine methylation levels in human hair may correlate with a cardiovascular biomarker in blood, suggesting hair sampling as a potential non-invasive method for cardiovascular risk assessment.
research A Prospective Real-World Study Evaluating Serum Levels of Arginine and Cysteine in Women With Chronic Telogen Effluvium: Do We Really Need Blanket Prescription of Amino Acid Supplementation?
This study suggests that arginine and cysteine deficiency is not present in women with chronic telogen effluvium, indicating that amino acid supplementation may be unnecessary in nutrient-replete populations.
research Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model
In this animal study, applying a combination of inositol-stabilized arginine silicate complex and magnesium biotinate promoted hair growth but not nail growth.
research The Effect of a Combination of an Arginine Silicate Complex and Magnesium Biotinate on Hair and Nail Growth in Rats
This study observed that a combination of arginine silicate complex and magnesium biotinate significantly improved hair and nail growth in rats.
research Arginine Metabolic Disruption Impairs Hair Regeneration via ROS-Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia
This study found that arginine deficiency in androgenetic alopecia patients is linked to increased oxidative stress and impaired hair follicle regeneration, with targeted arginine supplementation showing promise as a therapeutic strategy.
research Impaired Arginine Metabolism in Hair Follicles: A Potential Mechanism in Androgenetic Alopecia
This study found that androgenetic alopecia patients exhibited impaired arginine metabolism in balding hair follicles, suggesting that arginine supplementation may help preserve hair growth by counteracting mTOR signaling pathway disruption and offering potential as a treatment strategy.
research Clinical Study on the Efficacy and Tolerability of an Oral Supplement Based on Arginine, L-Cystine, Zinc and B6 Vitamin (Cystiphane) in Patients With Telogen Effluvium
In this study, researchers evaluated an oral supplement containing arginine, l-cystine, zinc, and vitamin B6, finding it effective as an adjuvant treatment for telogen effluvium, as indicated by improved hair quantity and diameter after three months in 18 patients.
research Comment on 'A Prospective Real World Study Evaluating Serum Levels of Arginine and Cysteine in Females With Chronic Telogen Effluvium: Do We Really Need Blanket Prescription With Amino Acid Supplementation?'
This study found that serum cysteine levels were not lower in patients with chronic telogen effluvium and did not correlate with hair loss severity.
research Hair Strengthening Evaluation of Anisotropic Osmolyte Solutions (Inositol + Arginine): Cross-Talk Between Dermal Papilla Fibroblast and Keratinocytes of the Outer Root Sheath Using a Micro Hair Follicle 3D Model
This study found that anisotropic osmolyte solutions may improve hair follicle turnover and condition in both in vitro and in silico models, as well as in human volunteers with hair disorders.
research Aminogenic Alopecia: Loss of Hair Associated with Argininosuccinic Aciduria
Argininosuccinic aciduria can cause hair loss.
research The Transdermal Inhibition of Melanogenesis by a Cell-Membrane-Permeable Peptide Delivery System Based on Poly-Arginine
This study found that the 11R-No. 10 peptide, delivered transdermally, significantly inhibited melanogenesis and produced a whitening effect in a UV-induced sun-tanning guinea pig model without cytotoxicity.
research Effects of Alpha-Melanocyte-Stimulating Hormone and [8-Arginine]-Vasotocin on Melanogenesis in Hair Follicle Melanocytes In Vitro
This study found that α-melanocyte-stimulating hormone increased melanin production in hair follicles of moulting Siberian hamsters, whereas [8-arginine]-vasotocin inhibited melanin production without affecting tyrosinase activity.
research A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis That Catalyzes the Peptidyl-Arginine-Citrulline Post-Translational Modification
This study focuses on improving the detection and characterization of an enzyme in guinea pig hair follicles that converts arginine to citrulline, highlighting challenges with assay sensitivity and reproducibility.
research Pathogenic Variants Affecting Peptidyl Arginine Deiminase 3 and Its Major Substrates Underlie Central Centrifugal Cicatricial Alopecia
This study identified nine pathogenic variants in the PADI3 gene and variants in the S100A3 and TCHH genes in patients with central centrifugal cicatricial alopecia, suggesting a broader genetic basis for the disease and potential targets for genetic testing and therapies.