3 citations
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October 2018 in “Revista de Chimie” This review discusses the potential medicinal properties and pharmacokinetic features of nettle compounds ursolic acid and quercetin, highlighting quercetin as a promising candidate for antioxidant and anti-aging effects, but reports no new clinical results.
January 2021 in “Natural Products Chemistry & Research” This study found that Datura metel leaf and flower extracts could improve hair growth, with leaf extracts prompting quicker growth and mixed extracts enhancing overall regrowth effectiveness in animal models.
May 2019 in “Journal of Drug Delivery and Therapeutics” In this study, a petroleum ether extract of Hemidesmus indicus seeds demonstrated hair growth-promoting effects in animal models, comparable to 2% minoxidil, by increasing the transition of hair follicles from telogen to anagen phase.
August 2019 in “Key engineering materials” This study found that Carthamus tinctorius floret extract, at a concentration of 0.05 mg/mL, significantly inhibited 5α-reductase activity in DU-145 cells more effectively than standard treatments finasteride and dutasteride, with a stable microemulsion formulation enhancing its skin permeation and stability.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a bael-based herbal shampoo formulation demonstrated effective cleansing, foaming ability, and stability, with antimicrobial properties that may benefit scalp health, positioning it as a promising natural alternative to synthetic shampoos.
August 2021 in “Majalah Obat Tradisional” This study found that a hair tonic formulated from green tea extract showed similar hair growth-promoting activity to 2% Minoxidil in rabbits, without causing skin irritation or bacterial contamination.
1 citations
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February 2022 in “International Journal of Health and Pharmaceutical (IJHP)” This study found that a combination of cantigi and henna leaf extracts, in a 1:2 ratio, demonstrated the strongest antioxidant activity with an IC50 value of 29.85 µg/mL.
5 citations
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September 2009 in “Journal of Complementary and Integrative Medicine” This study found that the petroleum ether extract of Citrullus colocynthis fruit and an isolated steroidal compound may reduce prostatic hyperplasia in rats induced by testosterone, suggesting potential use in managing androgen-dependent conditions.
February 2014 in “아시안뷰티화장품학술지” This review discusses various natural extracts, such as peppermint, rosemary, wild cultivated ginseng, and others, for their potential hair growth promotion effects and calls for further exploration into combinations with fewer side effects.
2 citations
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December 2009 In a mouse study, topical application of certain herbal extract mixtures showed accelerated hair regrowth compared to controls, with noted increases in specific enzyme activities and growth factors that may aid alopecia treatment.
January 2025 in “International Journal of Molecular Sciences” In this study, researchers found that fenugreek seed extract reduced prostate size, DHT levels, and cell proliferation in a testosterone-induced BPH rat model while modulating various genetic expressions, suggesting its potential as an alternative treatment for benign prostatic hyperplasia.
February 2019 in “Journal of Physiology & Pathology in Korean Medicine” In this study, the ethanol extract of Puerariae Radix was found to promote proliferation and ERK activation in human dermal fibroblasts, suggesting its potential as a new cosmetic ingredient.
10 citations
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January 2017 in “Journal of Evidence-Based Complementary & Alternative Medicine” This study found that several local vegetables from Northern Thailand demonstrated significant antioxidant and 5α-reductase inhibitory activities, suggesting their potential for development into health-promoting products.
February 2026 in “The Animal Biology” In this animal study, Hirudo verbana leech extract significantly improved hair follicle regeneration and accelerated wound healing in rats, demonstrating potential as a safe and effective agent for skin repair due to its bioactive compounds with regenerative and anti-inflammatory properties.
13 citations
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August 2020 in “Nutrients” This study found that GS-KG9 and GS-E3D, bioactive ginseng extracts, reduced BBB disruption and neuronal apoptosis in the hippocampus of diabetic rats, suggesting potential therapeutic effects for diabetic patients.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” This study found that Carthamus tinctorius floret ethanolic extract stimulated melanogenesis in B16F10 murine melanoma cells without cytotoxicity, suggesting its potential as a treatment for gray hair.
June 2023 in “CHEDS Journal of Chemistry Education and Science” In this experimental study, researchers developed a hair tonic using green spinach leaves and assessed its feasibility based on vitamin content and sensory characteristics, finding that the tonic was generally liked by panelists in hedonic tests.
1 citations
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January 2014 This study found that Crataegus pinnatifida extract promoted hair growth in mice by inducing the anagen phase, potentially through activating signaling pathways that enhance cell survival.
2 citations
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May 2023 in “Plants” In this study, Allium hookeri extract increased viability and size of dermal papilla cell spheroids and reduced oxidative stress effects, potentially promoting hair growth by regulating specific protein signaling pathways in human cells.
2 citations
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January 2018 in “Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches” In this study, red ginger extract gel showed stronger hair growth activity in male rats compared to a 2% minoxidil treatment, while white ginger extract was less effective.
In this study, applying a 5% concentration of pomegranate peel extract significantly enhanced hair growth on male rabbits, showing results comparable to the positive control using 2% Minoxidil, but higher concentrations or lower concentrations did not perform as well.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
1 citations
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January 2019 This article discusses various treatments for alopecia, including allopathic, homeopathic, and Ayurvedic methods, as well as the traditional use of certain herbs, but reports no new clinical results.
January 2017 in “한국약용작물학회지” This study suggests that 70% ethanol extracts from certain medicinal plants may promote hair growth and be useful for developing hair care products.
January 2017 in “Korean Journal of Pharmacognosy” This study found that pectin lyase-modified red ginseng extract may promote hair growth by enhancing antioxidant and anti-inflammatory activities, along with inhibiting testosterone-induced 5-alpha-reductase in human hair dermal papilla cells.
August 2024 in “Cosmetics” This study reported that peanut callus extract, rich in resveratrol, significantly stimulated hair growth and reduced hair loss in an in vitro model and a clinical trial, showing promise as a cosmetic bioactive ingredient.
November 2015 in “Indian drugs” This study found that the aerial roots of Ficus benghalensis Linn contain flavonoids, phenolics, and saponins, with an ethyl acetate extract being particularly rich in flavonoids.
37 citations
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January 1993 in “Yakugaku zasshi” This study found that a 70% ethanolic extract from Ginkgo biloba leaves promotes hair regrowth in C3H mice.
January 2020 in “Archives of Pharmacy Practice” This study found that Hibiscus rosa-sinensis leaf extract promoted hair growth in rats more effectively than its flower extract, suggesting its potential as a natural alternative for hair growth treatments.