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    Glossary Autophagy

    natural process where cells recycle their own components

    Autophagy is a natural process in which cells break down and recycle their own components. This helps to remove damaged or unnecessary parts, allowing the cell to maintain its health and function properly. For professionals, it's a crucial mechanism for cellular homeostasis and can be involved in responses to stress, nutrient deprivation, and even in the development of diseases like cancer and neurodegeneration.

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    1. Impaired turnover of autophagolysosomes in cathepsin L deficiency Biological Chemistry · 2010 · 113 citations
    2. Stimulation of Hair Growth by Small Molecules that Activate Autophagy Cell reports · 2019 · 88 citations
    3. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018 · 68 citations
    4. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation Autophagy · 2014 · 60 citations
    5. Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells Cell Death and Disease · 2020 · 52 citations
    6. Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture PLOS Biology · 2018 · 42 citations
    7. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    8. Inactivation of autophagy leads to changes in sebaceous gland morphology and function Experimental dermatology · 2018 · 27 citations
    9. BMP2-mediated PTEN enhancement promotes differentiation of hair follicle stem cells by inducing autophagy Experimental cell research · 2019 · 24 citations
    10. Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy Experimental Dermatology · 2019 · 20 citations
    11. Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update Mechanisms of Ageing and Development · 2018 · 19 citations
    12. A Connection between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis Journal of proteome research · 2008 · 14 citations
    13. Hydroxytyrosol prevents dermal papilla cells inflammation under oxidative stress by inducing autophagy Journal of Biochemical and Molecular Toxicology · 2019 · 13 citations
    14. Smart Nanosilver Strikes Twice: Precision Bacteria Killing Meets Autophagy‐Boosted Healing for Infected Wounds Advanced Functional Materials · 2025 · 11 citations
    15. Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice Frontiers in aging neuroscience · 2021 · 9 citations
    16. The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression Scientific reports · 2019 · 9 citations
    17. Isoquercitrin promotes hair growth through induction of autophagy and angiogenesis by targeting AMPK and IGF-1R Phytomedicine · 2024 · 8 citations
    18. Autophagy: Guardian of Skin Barrier Biomedicines · 2022 · 8 citations
    19. Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells Biomolecules & therapeutics · 2021 · 8 citations
    20. Autophagy-Mediated Cellular Remodeling during Terminal Differentiation of Keratinocytes in the Epidermis and Skin Appendages Cells · 2024 · 7 citations
    21. 5-Bromo-3,4-dihydroxybenzaldehyde Promotes Hair Growth through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells Molecules · 2022 · 7 citations
    22. Mechanisms of autophagy and their implications in dermatological disorders Frontiers in Immunology · 2024 · 6 citations
    23. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Autophagy · 2021 · 6 citations
    24. Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway Frontiers in Cell and Developmental Biology · 2021 · 5 citations
    25. ICP5249 Promotes Hair Growth by Activating the AMPK-Autophagy Signaling Pathway Journal of Microbiology and Biotechnology · 2024 · 5 citations
    26. Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen Journal of Dermatology · 2020 · 4 citations
    27. Folliculin Deficient Renal Cancer Cells Show Higher Radiosensitivity through Autophagic Cell Death 2014 · 4 citations
    28. Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation Autophagy · 2023 · 2 citations
    29. Autophagy Controls the Protein Composition of Hair Shafts 2023 · 2 citations
    30. Autophagy-related protein 12 associates with anti-apoptotic B cell lymphoma-2 to promote apoptosis in gentamicin-induced inner ear hair cell loss Molecular Medicine Reports · 2017 · 2 citations