Hydroxytyrosol Prevents Dermal Papilla Cells Inflammation Under Oxidative Stress by Inducing Autophagy

    July 2019 in “ Journal of Biochemical and Molecular Toxicology ”
    Qian Chen, Tao Sun, Jin Wang … Zhiqi Hu
    Studysummary In this study on rat dermal papilla cells, hydroxytyrosol, an antioxidant found in olive oil, was reported to protect against oxidative stress, reduce inflammation, and enhance hair growth factors, suggesting its potential to prevent hair loss.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Autophagy Is Essential for Maintaining the Growth of a Human Mini-Organ: Evidence from Scalp Hair Follicle Organ Culture PLOS Biology · 2018
    2. Mediterranean Diet: Fresh Herbs And Fresh Vegetables Decrease The Risk Of Androgenetic Alopecia In Males Archives of Dermatological Research · 2017
    3. Alopecia and the Metabolic Syndrome Clinics in Dermatology · 2017
    4. Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond? BioEssays · 2017
    5. Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells Methods in molecular biology · 2017
    6. Systemic Causes of Hair Loss Annals of Medicine · 2016
    7. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    8. Effect of a Nutritional Supplement on Hair Loss in Women Journal of Cosmetic Dermatology · 2015
    9. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    10. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated With p16INK4a Expression Journal of Investigative Dermatology · 2007
    11. The Additive Effects of Minoxidil and Retinol on Human Hair Growth In Vitro Biological & Pharmaceutical Bulletin · 2007
    12. Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    13. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    14. Treatment of Hair Loss The New England Journal of Medicine · 1999
    15. The Biology of Hair Follicles The New England Journal of Medicine · 1999