Effects of Nannochloropsis Salina Fermented Oil on Proliferation of Human Dermal Papilla Cells and Hair Growth

July 2024 in “ International Journal of Molecular Sciences ”

Ming Ying, Jialin Zhou, Zuye Zeng, Shuangfei Li, Xuewei Yang

Nannochloropsis salina fermented oil human dermal papilla cells hair growth eicosapentaenoic acid palmitic acid linoleic acid oxidative stress RNA-seq qRT-PCR minoxidil hair follicles dermal thickness NSO DPC Rogaine

From the encyclopedia

Omega 3 →

Linoleic Acid →

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary In this study, Nigella sativa oil was found to promote dermal papilla cell proliferation and may reduce oxidative stress, suggesting its potential as a hair loss intervention. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the effects of Nannochloropsis salina fermented oil (NSO) on human dermal papilla cells (DPCs) and hair growth. NSO, rich in eicosapentaenoic acid, palmitic acid, and linoleic acid, significantly promoted DPC proliferation, reduced oxidative damage, and upregulated antioxidant-related genes. In vivo experiments on C57BL/6 mice showed that topical NSO application increased hair length and weight, and histological analysis confirmed enhanced hair follicle number, depth, and thickness. These findings suggest NSO as a potential natural treatment for hair loss by promoting hair growth and mitigating oxidative stress.

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