Autophagy Critically Controls Skin Inflammation and Apoptosis-Induced Stem Cell Activation

    August 2023 in “ Autophagy
    Lisette Van Hove, Annagiada Toniolo, Mohammad Ghiasloo, Kim Lecomte, Fleur Boone, Maarten Ciers, Kris Raaijmakers, Niels Vandamme, Jana Roels, Sophia Maschalidi, Kodi S. Ravichandran, Maria Kasper, Geert Loo, Esther Hoste
    Image
    Studysummary In this study, researchers found that keratinocyte-specific deletion of the autophagy mediator Atg16l1 in mice heightened skin inflammation and cancer responses, altered hair follicle stem cell activity, and sensitized keratinocytes to cell death.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Discuss this study in the Community →

    Research cited in this study

    13 / 13 results