Plasticity of Epithelial Cells During Skin Wound Healing

    Xiaoyan Sun, Simon Joost, Maria Kasper
    Studysummary This review explores how epithelial cells from various niches in the skin respond and adapt during acute wound repair, highlighting the role of cellular plasticity in reepithelialization and restoring the skin's barrier function.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 25

    1. Hair Follicle Stem Cell Progeny Heal Blisters While Pausing Skin Development EMBO reports · 2021
    2. Cellular Heterogeneity and Microenvironmental Control of Skin Cancer Journal of Internal Medicine · 2020
    3. Stem Cell Dynamics, Migration, and Plasticity During Wound Healing Nature Cell Biology · 2018
    4. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations During Wound Healing Cell Reports · 2018
    5. Skin Cell Heterogeneity in Development, Wound Healing, and Cancer Trends in cell biology · 2018
    6. Homeostasis, Regeneration, And Tumor Formation In The Mammalian Epidermis The International Journal of Developmental Biology · 2018
    7. Skin Wound Healing in Humans and Mice: Challenges in Translational Research Journal of Dermatological Science · 2017
    8. Epithelial-To-Mesenchymal Transition in Cutaneous Wound Healing: Where We Are and Where We Are Heading Developmental Dynamics · 2017
    9. Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties Nature cell biology · 2017
    10. Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices Cell · 2017
    11. Defining Stem Cell Dynamics and Migration During Wound Healing in Mouse Skin Epidermis Nature Communications · 2017
    12. Hair Follicle and Interfollicular Epidermal Stem Cells Make Varying Contributions to Wound Regeneration Cell Cycle · 2015
    13. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    14. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin Cold Spring Harbor Perspectives in Medicine · 2014
    15. Plasticity of Epithelial Stem Cells in Tissue Regeneration Science · 2014
    16. Stem Cell Dynamics in the Hair Follicle Niche Seminars in Cell & Developmental Biology · 2013
    17. Spatial Organization Within a Niche as a Determinant of Stem-Cell Fate Nature · 2013
    18. Epithelial Stem Cells And Implications For Wound Repair Seminars in Cell & Developmental Biology · 2012
    19. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    20. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    21. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    22. Scratching the Surface of Skin Development Nature · 2007
    23. The Hair Cycle Journal of Cell Science · 2006
    24. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    25. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005