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Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

The authors maintain that shorter androgen receptor alleles may lead to milder COVID-19 by positively affecting the immune response, not due to changes in testosterone levels or activity.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

A gene called HDAC9 might be a new factor in male-pattern baldness.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Mutations in certain receptors can cause diseases and offer new treatment options.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

The HR protein's role as a repressor is essential for controlling hair growth.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.