12 citations
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September 2015 in “Drug Design Development and Therapy” This study found that the DOX derivative AD198 more effectively inhibited cell viability and induced apoptosis in canine cancer cell lines K9TCC and K9OSA compared to DOX in vitro.
December 2023 in “JEADV Clinical Practice” This study found that dermoscopy of the axilla in patients with frontal fibrosing alopecia revealed significantly higher odds of brownish peripillary halos, suggesting a diagnostic clue for the condition in this region.
September 2020 in “Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi” This review investigates the relationship between certain gene polymorphisms associated with obesity (FTO and MC4R) and Polycystic Ovarian Syndrome, reporting no new results but suggesting a potential genetic link.
2 citations
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October 2021 in “Bioinformation” This study found that the FTO gene variants rs17817449 and rs1421085 were significantly associated with PCOS susceptibility, and rs8050136 was linked with hair loss and high BMI in women with PCOS in western Saudi Arabia.
1 citations
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January 2020 in “Surgical & Cosmetic Dermatology” This article examines the potential of using oral minoxidil as an adjuvant treatment for patients with severe alopecia areata who do not respond to increased doses of Janus kinase inhibitors, but provides no new clinical results.
June 2025 in “Molecular Therapy — Nucleic Acids” In this study, researchers identified a specific DNA aptamer, Ap.OR2AT4.17, that effectively prolonged hair growth and increased hair shaft elongation in organ-cultured human hair follicles by targeting the olfactory receptor OR2AT4. This finding suggests the aptamer's potential as a novel therapy for hair loss disorders.
2 citations
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November 2017 in “Gynecological Endocrinology” This study found that serum myo-inositol oxygenase levels do not differ between women with polycystic ovary syndrome and healthy controls, suggesting that MI deficiency in PCOS is not due to MIOX levels.
November 2024 in “Advances in Pharmacology and Pharmacy” This study validated a UV-spectrophotometric method for accurately detecting Minoxidil and Tofacitinib citrate concentrations in bulk and gel formulations for alopecia areata, showing high recovery rates and indicating the method's suitability for routine analysis.
19 citations
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January 2020 in “Journal of Biophotonics” This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.
February 2025 in “Actas Dermo-Sifiliográficas” This study found that oral minoxidil can improve hair and eyebrow growth and increase the density of the frontotemporal hairline in patients with FFA, though adverse effects were reported by a third of participants.
10 citations
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September 2004 in “PubMed” In this study, no significant association was found between the VDR FokI gene polymorphism and alopecia areata, though further research in diverse populations is needed.
23 citations
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October 2008 in “Journal of medicinal chemistry” This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.
31 citations
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January 2016 in “Skin Appendage Disorders” This study observed two cases of frontal fibrosing alopecia developing on preexisting vitiligo, suggesting a potential causal link between the two conditions.
1 citations
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January 2010 This study found that ornithine decarboxylase (ODC) may play a significant role in regulating human hair growth and hair cycle changes, as inhibiting ODC reduced follicular keratinocyte proliferation and human hair growth.
This study concluded that the combination of all-trans-retinoic acid and tocopherol-α is not recommended for treating del(5q) myelodysplastic syndromes due to low efficacy and high incidence of adverse effects.
15 citations
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February 2021 in “Scientific Reports” This study found that novel RNA aptamers specifically inhibited FGF5-induced cell proliferation, suggesting their potential as candidates for treating FGF5-related diseases or hair disorders.
1 citations
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December 2017 in “Anais Brasileiros de Dermatologia” This article discusses the DOAJ, a comprehensive index of international open access journals, and emphasizes its role in providing free quality content online without presenting new research findings.
May 2025 in “Frontiers in Pharmacology” This study investigated alopecia areata in a mouse model, finding that tofacitinib may inhibit disease progression by modulating linoleic acid metabolism and magnesium pathways, particularly affecting CD8+ T cell infiltration in hair follicles, offering insights for potential treatments.
September 2023 in “Journal of the American Academy of Dermatology” This meta-analysis found a significant positive association between frontal fibrosing alopecia and both sunscreen and moisturizer use, with the moisturizer association significant only in males.
December 2022 in “Ecological Chemistry and Engineering S” This study synthesized indole-acenaphthylene compounds using a magnetic nanocatalyst and explored their photoluminescence properties for detecting copper ions in a mixed solvent system, achieving a detection limit of 9.5 ∙ 10 –6 M.
74 citations
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April 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study classified frontal fibrosing alopecia patients into three clinical patterns, finding that pattern III had the best prognosis and pattern II the worst after treatment with dutasteride and corticosteroids.
May 2023 in “Authorea (Authorea)” In this report, researchers documented a rare complication linked to levofloxacin, used as a second-line treatment for tuberculosis, which could include various adverse events during TB therapy.
June 2026 in “Virtual and Physical Prototyping” This study introduced a high-viscosity epoxy photoresist to enhance the fabrication of complex microstructures with monolithic integration and mechanical stability, enabling advancements in two-photon 3D printing for creating functional micro-mechanical devices.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study used molecular docking to analyze the binding affinities of quercetin and kaempferol, plant-derived flavonoids, showing they have promising interaction profiles with JAK3 kinase and moderate binding with 5-alpha reductase type 2, suggesting potential as topical treatments for androgenetic alopecia.
November 2022 in “SAS journal of medicine” This study found that serum ferritin levels were significantly higher in Jordanian patients with alopecia areata compared to controls, but still within the normal range.
21 citations
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September 2011 in “Journal of Pharmaceutical Sciences” This study found that the desolvation of finasteride hydrate solvates is highly dependent on the physical environment, complicating investigations but providing insight through complementary analysis techniques.
65 citations
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February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” This paper discusses the hypothesis that anti-acne agents may work by reducing FGFR2 signaling, and emphasizes FGFR2's potential role in acne pathogenesis, but it reports no new experimental findings.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports the discovery of LX-38, a new high-affinity non-steroidal antagonist that could provide the therapeutic benefits of current BPH and AGA treatments without the hormonal side effects, utilizing a distinct "Orthogonal T-Stacking" scaffold for binding.
January 2009 in “Xiandai huagong” This research outlines a chemical synthesis process for Finasteride, detailing the conversion of pregnadienolone acetate through various chemical reactions and modifications.
3 citations
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September 2024 in “BMC Oral Health” This study found that low-level laser therapy effectively reduced relapse rates, while functional appliances did not; combining them offered no additional benefits.