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This study describes the synthesis of finasteride from 4-androstene-3,17-dione in a seven-step process with an overall yield of 18.6%.

In a mouse model of chemotherapy-induced alopecia, this study found that inhibiting the protein S100A8 with paquinimod alleviated hair loss and reduced oxidative stress and ferroptosis, suggesting a potential therapeutic strategy for managing this side effect in chemotherapy patients.

Linalool in fragrances may harm hair follicles and contribute to hair loss.

This study examined the relationship between asprosin levels and polycystic ovary syndrome, finding no statistically significant difference in asprosin levels between patients and healthy controls, although differences in fetuin a levels were significant.

This article summarizes dermatologic adverse events in patients treated with afatinib in clinical trials and discusses strategies for managing these side effects, without providing new clinical results.

This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.

This study observed similar D2-40 expression in scarring and nonscarring alopecia, with some increase in scarring cases, suggesting possible Fos-dependent mechanisms, though more research is needed for definitive conclusions.

This study found that patients with alopecia areata had higher serum osteopontin levels and more eye abnormalities compared to healthy controls, although visual acuity was not affected.

This study characterized the SARM PF-05314882, finding it demonstrates anabolic activity in rats with minimal effects on the prostate, seminal vesicles, and luteinizing hormone levels.

This study suggests that polyamines regulate CK2 enzyme activity and its subcellular distribution, as demonstrated in mouse models and cell cultures with elevated levels of ornithine decarboxylase.

This study observed that carboxytherapy significantly improved clinical and dermoscopic measures in patients with alopecia areata and androgenetic alopecia compared to placebo, though some benefits regressed during follow-up.

This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.

This study found that the hair interior defect in AKR/J mice is linked to a mutation in the Soat1 gene, which disrupts SOAT1 protein expression and affects lipid metabolism critical for normal hair formation.

This study suggests that the transcription factor PDF2 in Arabidopsis may link lipid sensing with growth responses to phosphate starvation by acting as a sensor for lyso-PCs through its START domain.

This article reviews frontal fibrosing alopecia, exploring its characteristics, demographics, and associated conditions, and calls for controlled trials due to an increase in worldwide cases; it reports no new findings.

Authors retracted paper due to errors in data and mislabeling.

This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.

This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.

This study reported that while no synthesized compounds surpassed finasteride in 5α-reductase inhibitory activity, certain 4-azasteroid-2-oximes exhibited notable inhibition.

In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.

This study found that combining ablative fractional CO2 laser treatment with topical minoxidil significantly improved frontal hairline regrowth and patient satisfaction in men with androgenetic alopecia compared to using minoxidil alone, without serious adverse effects.

In this study, researchers developed a hierarchically engineered microreactor that effectively combats infected wounds by releasing antimicrobials at acidic sites, eradicating MRSA while avoiding resistance, and enhancing tissue repair through immune system modulation.

This study evaluated laser excision of the fibrous band for oral submucous fibrosis treatment, noting that while it offers immediate relief, long-term effects require further evaluation due to potential drawbacks.

This study developed a novel smart deoxyribozyme-based fluorescent sensor that efficiently detects androgen receptor mRNA with high selectivity and can be adapted to target various nucleic acid sequences.

This study explores how Astragaloside A from traditional Chinese medicine may combat lung adenocarcinoma by regulating key signaling molecules like STAT3 and AKT, using techniques such as network pharmacology and molecular docking to understand its mechanisms in cellular models.

This study reports three cases of alopecia areata resistant to corticosteroids that improved after 16 weeks of treatment with a combination of fractional carbon dioxide laser and topical tacrolimus, suggesting a potential new therapeutic option that requires further confirmation.

This study found that androstenedione was more effective than testosterone in diagnosing hyperandrogenism in women with PCOS when measured by LC-MS/MS.

This study adds evidence suggesting a genetic component to frontal fibrosing alopecia, with daughters experiencing an earlier onset than their mothers, although the clinical pattern remains similar to non-familial cases.

This study found that alopecia areata patients have elevated oxidative stress markers, such as OSI and MDA, and reduced antioxidant enzyme activities, suggesting a significant role for oxidative stress in the disease and potential value in targeting it therapeutically.