Fractionated CO2 Laser in Combination with Topical Tacrolimus for Chronic Alopecia Areata: A Case Series Study

    September 2024 in “ Life
    Giulio Rizzetto, Edoardo De Simoni, Helena Gioacchini … Oriana Simonetti
    Studysummary This study reports three cases of alopecia areata resistant to corticosteroids that improved after 16 weeks of treatment with a combination of fractional carbon dioxide laser and topical tacrolimus, suggesting a potential new therapeutic option that requires further confirmation.
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    Research cited in this study 14

    1. A Comparative Study of Fractional CO2 Laser with Topical Triamcinolone Acetonide Versus Intralesional Triamcinolone Acetonide in the Treatment of Alopecia Areata Journal of Cutaneous and Aesthetic Surgery · 2024
    2. Fractional Carbon Dioxide Laser Alone and as an Assisted Drug Delivery for Treatment of Alopecia Areata: A Clinical, Dermoscopic and Immunohistochemical Study Archives of Dermatological Research · 2023
    3. Comparative Evaluation of the Efficacy of Topical Tacrolimus 0.03% and Topical Calcipotriol 0.005% Mixed With Betamethasone Dipropionate Versus Topical Clobetasol 0.05% in Treatment of Alopecia Areata: A Clinical and Trichoscopic Study Journal of cosmetic dermatology · 2022
    4. Evaluation of Fractional Carbon Dioxide Laser Alone Versus Its Combination With Betamethasone Valerate in Treatment of Alopecia Areata: A Clinical and Dermoscopic Study Archives of dermatological research · 2022
    5. Comparative Study Between Fractional Carbon Dioxide Laser vs Intralesional Steroid Injection in Treatment of Alopecia Areata Dermatologic Therapy · 2020
    6. Efficacy of Different Concentrations of Intralesional Triamcinolone Acetonide for Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2019
    7. Italian Guidelines in Diagnosis and Treatment of Alopecia Areata Giornale italiano di dermatologia e venereologia · 2019
    8. Fractional Laser-Assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review Cureus · 2019
    9. The Effect of the Fractional Carbon Dioxide Laser on Improving Minoxidil Delivery for the Treatment of Androgenetic Alopecia Journal of lasers in medical sciences · 2019
    10. Alopecia Areata: A Review of Disease Pathogenesis British journal of dermatology/British journal of dermatology, Supplement · 2018
    11. Clinical Effects of Non-Ablative and Ablative Fractional Lasers on Various Hair Disorders: A Case Series of 17 Patients Journal of Cosmetic and Laser Therapy · 2013
    12. Dermoscopic Evaluation of Therapeutic Response to an Intralesional Corticosteroid in the Treatment of Alopecia Areata Indian Journal of Dermatology, Venereology and Leprology · 2013
    13. Histopathology of Alopecia: A Clinicopathological Approach to Diagnosis Histopathology · 2009
    14. Expression of Vascular Endothelial Growth Factor, Apoptosis Inhibitors (Survivin and p16) and CCL27 in Alopecia Areata Before and After Diphencyprone Treatment: An Immunohistochemical Study British Journal of Dermatology · 2004

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019