Evaluation of Fractional Carbon Dioxide Laser Alone Versus Its Combination With Betamethasone Valerate in Treatment of Alopecia Areata: A Clinical and Dermoscopic Study

September 2022 in “ Archives of dermatological research ”

Dalia Abdel Halim, Mariam Nayer, Solwan I El-Samanoudy, Heba Mohamed Abdel Raheem, Nanis Ragab

fractional carbon dioxide laser betamethasone valerate alopecia areata SALT score dystrophic hair terminal hair FRCO2 laser betamethasone cream AA

TLDR The fractional carbon dioxide laser is a safe and effective treatment for alopecia areata and works better than betamethasone valerate cream alone.

The study evaluated the efficacy and safety of fractional carbon dioxide (FRCO2) laser treatment for alopecia areata (AA), both alone and in combination with betamethasone valerate cream, compared to the cream alone. It involved 30 patients divided into three groups, with treatments over a 4-month period consisting of eight laser sessions at 2-week intervals. Results showed a significant decrease in Severity of Alopecia Tool (SALT) score and dystrophic hair, and an increase in terminal hair across all groups. Patient satisfaction and SALT score reduction were significantly higher in the groups treated with FRCO2 laser, with or without the cream. However, there was no significant difference between the FRCO2 laser alone and the combination treatment. The study concluded that FRCO2 laser is a safe and effective treatment for AA and is superior to betamethasone valerate cream monotherapy.

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