Comparative Study Between Ablative Fractional Carbon Dioxide Laser Combined With Topical Steroid Versus Topical Steroid in Treatment of Alopecia Areata
October 2025
in “
Iraqi postgraduate medical journal
”
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Studysummary This study observed that using fractional CO2 laser-assisted delivery of clobetasol propionate cream significantly improved treatment outcomes for localized alopecia areata compared to the cream alone, suggesting the laser's enhancing effect on hair regrowth.
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This study evaluated the effectiveness of combining fractional carbon dioxide laser with topical steroid clobetasol propionate 0.05% cream in treating alopecia areata. Involving 20 patients with 108 patches, the study compared two groups: one receiving both laser treatment and cream (Group A) and the other receiving only the cream (Group B). Over four sessions at two-week intervals, Group A showed significantly better treatment outcomes than Group B. The results suggest that fractional CO2 laser combined with clobetasol propionate cream is a more effective treatment for localized alopecia areata than the cream alone.