New Approach to 3-Oxo-4-Aza-5α-Androst-1-Ene-17β-(N-Tert-Butylcarboxamide)

    May 2005 in “ Steroids ”
    Zhong‐Ping Jiang, Jing Ye, Ling Jiang, Yunyun Zhao
    Studysummary This study describes the synthesis of finasteride from 4-androstene-3,17-dione in a seven-step process with an overall yield of 18.6%.
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    Research cited in this study 4

    1. New Synthesis of Finasteride Chinese Journal of Pharmaceuticals · 2003
    2. Finasteride and the Hair Cycle Journal of The American Academy of Dermatology · 2000
    3. Androgenetic Alopecia: Finasteride Treated Hair Loss PubMed · 1999
    4. Synthesis of N-Substituted 3-Oxo-17b-Carboxamide-4-Aza-5a-Androstanes and the Tautomerism of 3-Oxo-4-Aza-5-Androstenes Heterocycles · 1998