A Smart Deoxyribozyme-Based Fluorescent Sensor for In Vitro Detection of Androgen Receptor mRNA

May 2020 in “ Beilstein Journal of Organic Chemistry ”

Ekaterina A. Bryushkova, Erik Gandalipov, Julia Victorovna Nuzhina

androgen receptor mRNA deoxyribozyme fluorescent sensor malachite green aptamer oligonucleotide platform RNA fragment mRNA human dermal papilla cells AR mRNA SDFS malachite green dye

Studysummary This study developed a novel smart deoxyribozyme-based fluorescent sensor that efficiently detects androgen receptor mRNA with high selectivity and can be adapted to target various nucleic acid sequences.

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research Increased Androgen Receptor Messenger RNA in Frontal-Parietal Hair Follicles of Women with Androgenetic Alopecia

6 citations , January 2013 in “Genetics and Molecular Research”

This study found that women with androgenetic alopecia demonstrated higher androgen receptor gene expression compared to controls, with a correlation found between higher AR expression and fewer CAG repeats in the AR gene.