TLDR A new easy-to-use biosensor was made to detect androgen receptor mRNA, which could help diagnose related conditions quickly.
In 2020, a novel Smart DNA Biosensor was developed for the primary diagnosis of androgen receptors overexpression, which can lead to conditions such as acne, androgenetic alopecia, or hirsutism. This biosensor, based on RNA-dependent split aptamer, was found to be easy to use, highly efficient and selective, and due to its modular structure, could be easily optimized for the detection of various targets. This development suggested that such sensors could be useful for rapid differential diagnosis, particularly in cases where traditional laboratory techniques are not available due to their complexity and laboriousness.
14 citations,
February 2016 in “Journal of Obstetrics and Gynaecology Research” Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.
1 citations,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
3 citations,
January 2012 in “Hanyang Medical Reviews” The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
85 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
1 citations,
April 1993 in “Problemy e̊ndokrinologii” Spironolactone effectively reduces symptoms of hyperandrogenism like hirsutism and acne.