TLDR Androstenedione is better than testosterone for diagnosing PCOS in Indian women.
This study found that androstenedione (A4) measured through liquid chromatography-mass spectrometry (LC-MS/MS) is more effective in diagnosing polycystic ovary syndrome (PCOS) in Indian women than testosterone (T). Elevated levels of A4 and dehydroepiandrosterone (DHEA) were observed in 75% of hyperandrogenic women with normal T levels. A4 had the highest diagnostic accuracy with an AUC of 0.89. The findings suggest that A4 is a valuable marker for diagnosing hyperandrogenism in PCOS, but further research on androgen profiles and their cost-effectiveness is needed.
Cited in this study
3 / 3 results
6 citations
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August 2023 in “European journal of endocrinology” The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.
883 citations
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August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
28 citations
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April 2014 in “Hormones” Higher androstenedione levels in women with PCOS are linked to more severe symptoms.
15 citations
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December 2016 in “Revista Da Associacao Medica Brasileira” Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.
10 citations
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November 2010 in “Skin therapy letter” Women with PCOS often have acne because of high androgen levels, and the article reviewed how to treat this type of acne.
212 citations
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September 2010 in “American Journal of Obstetrics and Gynecology” Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.
