Low-Dose Oral Minoxidil for Frontal Fibrosing Alopecia: A 122-Patient Case Series

    February 2025 in “ Actas Dermo-Sifiliográficas ”
    C. Pindado-Ortega, Rodrigo Pirmez, DanielFernandes Melo, L. Junqueira Fortes Binato, M.L. Porriño-Bustamante, J. Barreto Carpi, Rocío Gil‐Redondo, Ángela Hermosa‐Gelbard, Juan ­Jimenez‐Cauhe, David Saceda‐Corralo, Sergio Vañó‐Galván
    TLDR Low-dose oral minoxidil can help improve hair and eyebrow growth in people with frontal fibrosing alopecia.
    The study analyzed the effectiveness of low-dose oral minoxidil in treating frontal fibrosing alopecia (FFA) in a case series of 122 patients across centers in Brazil and Spain. Results showed that 45.1% of patients experienced improvement in the density of the frontotemporal hairline, with 34.4% showing mild, 9.0% moderate, and 1.6% excellent improvement. Additionally, 57.4% of patients saw improved hair density in the interparietal area, 25.4% experienced eyebrow growth, and 3.3% had eyelash growth. Adverse effects were reported in 33.6% of patients, with hypertrichosis being the most common at 23.8%. The study suggests that oral minoxidil can be an effective complementary therapy for FFA, enhancing hair and eyebrow growth and frontotemporal hairline density.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community So we’re just ok with taking a research chemical now?

      in Treatment  178 upvotes 3 years ago
      The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 10 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community Where to Begin with Microneedling?

      in Treatment  17 upvotes 1 year ago
      User is considering microneedling to enhance hair regrowth after limited response to minoxidil and better results with finasteride and ketoconazole shampoo. Recommendations include using a 1.5mm derma roller once a week, avoiding minoxidil on microneedling days, and disinfecting the roller with isopropyl alcohol.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  79 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

    Related Research

    1 / 1 results