Synthesis of a 4-Azasteroid Hormones Compound
January 2009
in “
Xiandai huagong
”
TLDR Finasteride was successfully synthesized from Pregnadienolone acetate.
The document detailed a synthetic process for creating a 4-azasteroid hormone compound, specifically Finasteride. The synthesis involved multiple chemical reactions starting with Pregnadienolone acetate, which was transformed through a series of steps including oxidation, esterification, and ring closure. The final step involved dehydrogenation of the A-ring to produce Finasteride.