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Glossary Oxidation

chemical process where a substance loses electrons

Oxidation is a chemical process where a substance loses electrons, often involving the interaction with oxygen. In the context of hair and biology, oxidation can affect hair color and strength, as it can lead to the breakdown of melanin (the pigment in hair) and the weakening of hair proteins, potentially contributing to conditions like alopecia.

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Research

5 / 1000+ results

research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review

280 citations , July 2018 in “Antioxidants”

This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.

research Senile hair graying: H ₂ O ₂ ‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair

217 citations , February 2009 in “The FASEB Journal”

This study found that hydrogen peroxide accumulation and reduced methionine sulfoxide repair play a significant role in the oxidative damage linked to senile hair graying.

research Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis

215 citations , March 2018 in “Archives of Toxicology”

This study found that PM2.5 exposure induced oxidative stress in human keratinocytes and mouse skin, causing cellular damage, which was mitigated by the antioxidant N-acetyl cysteine.

research Oxidative stress in ageing of hair

126 citations , January 2009 in “International Journal of Trichology”

This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.

research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

81 citations , November 2012 in “Journal of the National Cancer Institute”

This study found that FLCN deficiency in mice muscles led to increased mitochondrial biogenesis and a metabolic shift towards oxidative phosphorylation, with a similar advantage observed in FLCN-null kidney cancer cells.

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Community Join

5 / 109 results

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Minoxidil cannot survive summer in warehouses or UPS trucks

64 upvotes 1 month ago

Minoxidil's effectiveness may not be significantly impacted by high temperatures during shipping, as it undergoes stability tests to withstand extreme conditions. Users discuss concerns about oxidation and storage, but experts suggest that short-term exposure to heat is unlikely to degrade the product.

community Finasteride solution changing colors

in Finasteride/Dutasteride 1 upvotes 5 months ago

A user noticed a color change in their hair loss solution containing minoxidil, finasteride, retinoic acid, and hydrocortisone after storing it for several months. They are concerned about the effectiveness of the solution due to potential oxidation.

community A Study I came along by mistake researching (Dutasteride +Pumpkin seed oil ) for every other day use.

16 upvotes 3 months ago

Alternating Dutasteride with pumpkin seed oil may protect the spleen from damage caused by Dutasteride. Pumpkin seed oil's antioxidants help counteract oxidative stress and immune suppression.

community Does anyone know the chemical formula for pelage pp405?

15 upvotes 1 year ago

The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

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