Synthesis of Finasteride

    January 2007 in “ The Journal of Pharmaceutical Practice ”
    Qiuye Wu
    TLDR The process to make finasteride is simple, cheap, and gives a good amount.
    The study focused on the synthesis of finasteride from pregnenolone acetic ester using a series of chemical reactions, including hypobromous acid oxidation, methanol esterification, Oppenauer oxidation, and the Bodroux reaction. The overall yield of the synthesis was 36.5%. The researchers concluded that the materials used were inexpensive, the process was simple, the cost was low, and the yield was satisfactory.
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