research Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance
SCD1 is crucial for skin health and overall energy balance.
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900-930 / 1000+ resultsresearch A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis
Inhibiting ODC can prevent UV-induced skin cancer.
research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Identification and Characterization of Four Immune-Related Signatures in Keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research Eclipta Alba (Bhringraj): A Promising Hepatoprotective and Hair Growth Stimulating Herb
Eclipta alba (Bhringraj) helps protect the liver and promotes hair growth.
research Stimuli-Responsive Nanoformulations for CRISPR-Cas9 Genome Editing
Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
research Assessment of Heavy Metal and Trace Element Levels in Patients with Telogen Effluvium
Heavy metals might contribute to hair loss in Telogen Effluvium.
research Effects of Orlistat on Serum Androgen Levels Among Iranian Obese Women With Polycystic Ovarian Syndrome
Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
research Thermodynamically Stable Ionic Liquid Microemulsions for Topical Delivery and Peptide Application
New method improves copper peptide delivery for hair growth three times better than current options.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
research Human Teeth Are Useful Even After They Are Shed: Why Discard Them?
Baby teeth stem cells can potentially grow organs and treat diseases.
research CAQ Corner: Basic Concepts of Transplant Immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research Androgens’ Effects Across the Lifespan in Men and Animal Models
Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
research Trigonelline Nanocrystal-Based Topical Creams for the Treatment of Hair Loss
Trigonelline nanocrystal cream effectively promotes hair growth and may reduce side effects.
research Optimizing Nutrition for PCOS Management: A Comprehensive Guide
Proper nutrition can help manage PCOS symptoms and improve overall health.
research Innovative Approach for Polycystic Ovary Syndrome Treatment: Brown Adipose Tissue
Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
research Irritation Test and Hair Growth Activity of Usada Bali Plant-Based Hair Tonic on Mice
The hair tonic from Usada Bali plants increased hair growth without irritating the skin.
research Atypical Formations of Gintonin Lysophosphatidic Acids as New Materials and Their Beneficial Effects on Degenerative Diseases
New ginseng compounds may help treat degenerative diseases.
research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2
Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Autotaxin-LPA Signaling Contributes to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism
Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.
research SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice
SIRT7 protein is crucial for starting hair growth in mice.
research Desmoglein 4 Is Regulated by Transcription Factors Implicated in Hair Shaft Differentiation
Desmoglein 4 is controlled by specific proteins that affect hair growth.
research Effects of Lifelong Testosterone Exposure on Health and Disease Using Mendelian Randomization
Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles: Drug Loading Capacity and Cytotoxicity
Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.
research Toxicology and Pharmacology of Botulinum and Tetanus Neurotoxins: An Update
Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.