Search

everythinglearnresearchcommunity

for

Search:↓

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

Mutations in certain receptors can cause diseases and offer new treatment options.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Sebocytes play a key role in controlling androgen levels in human skin.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Treatment during development affects hormone balance and sexual behavior in male rats.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.