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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride safely lowers DHT levels without affecting testosterone.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.

The review suggests a comprehensive approach to treat hirsutism, focusing on hair removal, medication, and managing emotional effects.

Androgens can help prevent memory problems caused by apoE4.

Finasteride helps reduce heart issues and improves heart function.

RU 58841 may treat acne, hair loss, and excessive hair growth.

Men with Kennedy disease have less chance of hair loss.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

New compounds may soon be tested to treat excessive hair growth in women.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Using 3% topical minoxidil can help women with hair loss, but more research is needed.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

Fluridil safely promotes hair growth in men with androgenetic alopecia.

Fluridil safely promotes hair growth in men with androgenetic alopecia.