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    Glossary AKT1

    gene involved in cell growth and survival

    AKT1 is a gene that produces a protein involved in cell growth, survival, and metabolism. In simpler terms, it's like a switch that helps cells grow and stay alive. For professionals, AKT1 is a serine/threonine kinase that plays a critical role in the PI3K/AKT signaling pathway, which is often implicated in cancer and other diseases due to its role in promoting cell proliferation and inhibiting apoptosis.

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    Research 30 of 238

    1. Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis Cell Stem Cell · 2016 · 106 citations
    2. Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients Archives of Gynecology and Obstetrics · 2017 · 24 citations
    3. Transcriptomic Analysis Reveals AKT1 Upregulation in Inner Mongolian Cashmere Goats at 12 and 15 Months of Age Veterinary Sciences · 2026
    4. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF Nature Communications · 2017 · 117 citations
    5. Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930 Molecular cancer therapeutics · 2011 · 65 citations
    6. Effect of Scenedesmus deserticola JD052 Extracts on Hair Inductivity by Regulating the AKT and GSK3β/β-Catenin Signaling Pathways in Human Dermal Papilla Cells Applied Sciences · 2025
    7. Ginsenoside Rb1 promotes the growth of mink hair follicle via PI3K/AKT/GSK-3β signaling pathway Life Sciences · 2019 · 28 citations
    8. Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis Theranostics · 2024
    9. β-sitosterol in Yijing Hugui decoction prevents cyclophosphamide-induced premature ovarian insufficiency via the AKT1/Nrf2 pathway Cytotechnology · 2025 · 7 citations
    10. Natural Compounds Targeting MAPK, PI3K/Akt, and JAK/STAT Signaling in Papillary Thyroid Cancer International Journal of Molecular Sciences · 2025 · 1 citations
    11. Molecular Genetics of the PI3K-AKT-mTOR Pathway in Genodermatoses: Diagnostic Implications and Treatment Opportunities 2016 · 36 citations
    12. The common regulatory pathway of COVID-19 and multiple inflammatory diseases and the molecular mechanism of cepharanthine in the treatment of COVID-19 Frontiers in Pharmacology · 2022 · 15 citations
    13. The mechanism of activated platelet‐rich plasma supernatant promotion of hair growth by cultured dermal papilla cells Journal of Cosmetic Dermatology · 2019 · 14 citations
    14. Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos Journal of Cellular Physiology · 2019 · 7 citations
    15. Elucidating the anti-aging mechanism of Si Jun Zi Tang by integrating network pharmacology and experimental validation in vivo Aging · 2022 · 6 citations
    16. Effects of Baicalin on Alopecia and the Associated Mechanism BioMed Research International · 2022 · 2 citations
    17. Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression BMC chemistry · 2023 · 1 citations
    18. Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking Clinical, Cosmetic and Investigational Dermatology · 2022 · 1 citations
    19. [The effect of cgVEGF164 on the growth of murine hair follicles]. PubMed · 2019 · 1 citations
    20. Baicalin Against Androgenetic Alopecia: A Network Pharmacology Study 2025
    21. Lipidomics Combined with Network Pharmacology to Explore Differences in the Mechanisms of Grey Hair Development Between Type 2 Diabetes Mellitus and Normal Populations (Female) International Journal of Molecular Sciences · 2025
    22. Network Pharmacology Reveals Curcuma aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia Biology · 2024
    23. Treatment of androgenetic alopecia by exosomes secreted from hair papilla cells and the intervention effect of LTF Journal of Cosmetic Dermatology · 2023
    24. Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens against E2F1-Driven Melanoma Progression 2023
    25. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020 · 25 citations
    26. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    27. Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth The Korean Journal of Physiology and Pharmacology · 2018 · 21 citations
    28. Hair Growth Promoting Effect of <i>Hottuynia cordata</i> Extract in Cultured Human Hair Follicle Dermal Papilla Cells Biological & Pharmaceutical Bulletin · 2019 · 16 citations
    29. Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle Experimental Dermatology · 2021 · 14 citations
    30. Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways Frontiers in pharmacology · 2018 · 14 citations