Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers

    October 2010 in “ Oncogene ”
    Vassiliki Karantza
    Studysummary This review discusses the role of keratins in epithelial cell stress protection and cancer, highlighting their potential as multifunctional regulators and diagnostic markers, without presenting new research findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 5

    1. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    2. Epidermal Abnormalities and Increased Malignancy of Skin Tumors in Human Epidermal Keratin 8-Expressing Transgenic Mice The FASEB Journal · 2004
    3. Type II Keratins Are Phosphorylated on a Unique Motif During Stress and Mitosis in Tissues and Cultured Cells Molecular Biology of the Cell · 2002
    4. Hard and Soft Principles Defining the Structure, Function, and Regulation of Keratin Intermediate Filaments Current Opinion in Cell Biology · 2002
    5. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998