The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis

    October 2024 in “ Frontiers in Oncology ”
    Jia‐Zhi Yan, Ankui Yang, Shuo Tu
    Studysummary This review examines the potential of K18 as a diagnostic and prognostic marker in epithelial-derived tumors, highlighting its specific expression in tumor tissues and interaction with proteins involved in tumor progression, without reporting new clinical findings.
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    Research cited in this study 4

    1. Types I and II Keratin Intermediate Filaments Cold Spring Harbor Perspectives in Biology · 2018
    2. Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers Oncogene · 2010
    3. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    4. Hard and Soft Principles Defining the Structure, Function, and Regulation of Keratin Intermediate Filaments Current Opinion in Cell Biology · 2002

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    1. The Extraction And Characterization Of Human Nail Keratin Journal of Dermatological Science · 1991