Type II Keratins Are Phosphorylated on a Unique Motif During Stress and Mitosis in Tissues and Cultured Cells

    June 2002 in “ Molecular Biology of the Cell ”
    Diana M. Toivola, Qin Zhou, Luc S. English, M. Bishr Omary
    Studysummary This study found that type II keratins in proliferating epithelial tissues are phosphorylated at a conserved motif during mitosis and stress, impacting keratin solubilization and reorganization.
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    Research cited in this study 9

    1. Hard and Soft Principles Defining the Structure, Function, and Regulation of Keratin Intermediate Filaments Current Opinion in Cell Biology · 2002
    2. A Novel Type II Cytokeratin, mK6irs, Is Expressed in the Huxley and Henle Layers of the Mouse Inner Root Sheath Journal of Investigative Dermatology · 2001
    3. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    4. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    5. The Two Functional Keratin 6 Genes of Mouse Are Differentially Regulated and Evolved Independently from Their Human Orthologs Genomics · 1998
    6. Biochemical and Immunohistochemical Analyses of Keratin Expression in Basal Cell Carcinoma Journal of Dermatological Science · 1998
    7. Keratin and Skin Disorders Cell biology international · 1996
    8. Suprabasal Change and Subsequent Formation of Disulfide-Stabilized Homo- and Hetero-Dimers of Keratins During Esophageal Epithelial Differentiation Journal of Cell Science · 1993
    9. Hair Follicle Differentiation: Expression, Structure, and Evolutionary Conservation of the Hair Type II Keratin Intermediate Filament Gene Family Development · 1992

    Related research 1

    1. Hard and Soft Principles Defining the Structure, Function, and Regulation of Keratin Intermediate Filaments Current Opinion in Cell Biology · 2002