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GlossaryAKT3

gene involved in cell growth and survival

AKT3 is a gene that encodes a protein involved in cell growth, survival, and metabolism. It is one of the three isoforms of the AKT kinase family, which play a crucial role in signaling pathways that regulate these cellular processes. Mutations or dysregulation of AKT3 can be associated with various conditions, including cancer and certain types of alopecia, where it may affect hair follicle function and growth.

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research Protein Kinase Akt2/PKBβ Is Involved in Blastomere Proliferation of Preimplantation Mouse Embryos

7 citations, September 2019 in “Journal of Cellular Physiology”

Akt2 protein is essential for normal cell division in early mouse embryos.

research News in Brief

June 2011 in “Expert Review of Dermatology”

Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.

research Expression of AKT1 Along with AKT2 in Granulosa-Lutein Cells of Hyperandrogenic PCOS Patients

24 citations, March 2017 in “Archives of Gynecology and Obstetrics”

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

research Cell Death in the Skin: Mechanisms and Implications

120 citations, February 2009 in “Apoptosis”

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

research FOXO1, TGF-β Regulation and Wound Healing

87 citations, September 2014 in “International Journal of Molecular Sciences”

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

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