58 citations
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January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.
May 2023 in “Plastic and reconstructive surgery. Global open” This study reviewed 29 clinical studies on autologous activated PRP injections for alopecia and found that 27 studies reported significant improvements in hair density, regrowth, and reduction in hair loss, demonstrating potential effectiveness as a treatment for hair loss.
March 2023 in “Aesthetic Surgery Journal” This systematic review and meta-analysis found that activated platelet-rich plasma was significantly effective and safe in improving hair density and reducing hair loss in alopecia patients compared to control groups.
183 citations
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January 2014 in “BioMed Research International” This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.
136 citations
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February 2017 in “International Journal of Molecular Sciences” This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.
January 2025 in “Open Science Framework” AA-PRP temporarily increases hair density in androgenetic alopecia but loses effectiveness over time.
44 citations
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February 2020 in “Expert Opinion on Biological Therapy” In this study, autologous non-activated platelet-rich plasma was associated with greater hair re-growth than autologous activated platelet-rich plasma over long-term follow-up.
July 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” AA-PRP injections significantly promote hair growth but need better study design for clear efficacy.
September 2026 in “Aesthetic Surgery Journal” This study found that autologous non-activated platelet-rich plasma (A-PRP) was effective and safe for treating androgenetic alopecia, showing long-term improvement in hair density, thickness, and count.
24 citations
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November 2017 in “Aesthetic Plastic Surgery” In this study, researchers found that homologous PRP (h-PRP) significantly increased hair density more than both nonactivated (n-PRP) and activated (a-PRP) autologous PRP in patients with androgenetic alopecia, suggesting h-PRP as a potentially more effective treatment option for hair loss.
2 citations
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October 2022 in “Skin appendage disorders” This study found that platelet rich plasma (PRP) is a safe and effective treatment for alopecia areata, with no significant difference in efficacy between activated and non-activated PRP.
July 2024 in “Journal of Investigative Dermatology” PRP preparation partially activates platelets, causing varied growth factor release.
January 2023 in “Indian Journal of Dermatology, Venereology and Leprology” In this study, activated platelet-rich plasma improved hair density and thickness in patients with androgenetic alopecia, with higher platelet counts enhancing these effects over time.
March 2021 in “Türk plastik cerrahi dergisi” In this study, activated platelet-rich plasma injections significantly increased hair count, density, and the anagen/telogen ratio in men with androgenetic alopecia, compared to placebo, suggesting it as a safe alternative to medical treatments for early-stage alopecia.
52 citations
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May 2017 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections significantly improved hair density, thickness, and patient satisfaction in women with female pattern hair loss compared to a placebo.
7 citations
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December 2016 in “Journal of The Taiwan Institute of Chemical Engineers” This study found that porcine platelet-rich plasma can be a commercially viable replacement for fetal bovine serum with similar effectiveness in promoting human hair follicle cell growth.
6 citations
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May 2021 in “Journal of Health Sciences” In this study, researchers administered intravenous autologous activated platelet-rich plasma (aaPRP) to 611 patients and reported no adverse events, suggesting that this treatment is safe even for patients with various pathological conditions.
4 citations
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September 2020 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections promote hair growth and are safe and effective for treating androgenetic alopecia.
4 citations
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October 2019 in “Skin appendage disorders” This study found that autologous activated PRP injections significantly increased hair density in patients with androgenetic alopecia, with patients reporting high satisfaction and few side effects.
January 2020 in “Majalah Kedokteran Gigi Indonesia” The researchers reported that freeze-dried collagen-activated platelet-rich plasma increased transforming growth factor-β1 levels compared to non freeze-dried PRP with collagen, suggesting a potential benefit for tissue regeneration.
3 citations
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June 2017 in “PubMed” In this study, autologous platelet-rich plasma prepared with Merisis One Step Gel Separation Technology improved hair counts, thickness, root strength, and overall alopecia in five patients without major adverse effects over three months.
February 2020 in “Int J Biologicals” This study found that super-activated platelet lysate increased hair follicle density in a mouse model of androgenetic alopecia, outperforming platelet-rich plasma and platelet lysate.
20 citations
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July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
16 citations
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December 2019 in “Journal of Cellular and Molecular Medicine” This study found that sonicated platelet-rich plasma was more effective than calcium chloride-induced platelet-rich plasma in activating hair follicle stem cells and promoting hair follicle regeneration in mice.
14 citations
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March 2019 in “Journal of Cosmetic Dermatology” This laboratory study found that activated platelet‐rich plasma supernatant enhanced hair growth signaling pathways in cultured human dermal papilla cells, suggesting potential for treating androgenic alopecia.
January 2022 in “Figshare” This study found that platelet-rich plasma is a safe, effective, and well-tolerated treatment for alopecia areata, with no significant difference between activated and non-activated PRP.
February 2017 in “Spectrum Research Repository (Concordia University)” This study confirmed porcine PRP's commercial viability as a fetal bovine serum replacement, showing higher growth factor levels and stability, without increasing human follicle dermal papilla cell proliferation compared to FBS.
June 2022 in “Biotechnological Research” This review discusses the potential of activated autologous platelet-rich plasma (aaPRP) for improving diabetic foot ulcer outcomes but reports no new clinical results, noting the need for further evidence.
31 citations
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March 2020 in “International Journal of Regenerative Medicine” This study found that intraovarian PRP treatment in women with low ovarian reserve was associated with significant increases in serum AMH levels in some patients, typically within four weeks.
1 citations
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January 2021 in “European journal of medical and health sciences” This review proposes a treatment protocol for androgenetic alopecia using platelet-rich plasma, but reports no new clinical results, highlighting the need for standardized preparation and assessment methods.