Activated Platelet Rich Plasma Versus Non-Activated Platelet Rich Plasma in the Treatment of Alopecia Areata

October 2022 in “ Skin appendage disorders ”

Ahmed H. Nouh, Ahmed M. Abdelaal, Ali El Sayed Fathy

platelet-rich plasma PRP alopecia areata AA activated PRP non-activated PRP intradermal PRP treatments

TLDR Activated and non-activated PRP are equally safe and effective for treating alopecia areata.

The study compared the effectiveness of activated versus non-activated platelet-rich plasma (PRP) in treating alopecia areata (AA) in 40 subjects. Both groups received 4 intradermal PRP treatments, with one group receiving activated PRP and the other non-activated PRP. Results showed no statistically significant difference in improvement between the two groups, indicating that PRP activation is not necessary for effective AA treatment. Both methods were found to be safe, effective, and well-tolerated, with no patients experiencing worsened conditions. The study concludes that PRP is a cost-effective treatment option for AA that can be administered in outpatient settings without the need for expensive preparation tools.

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