Hair Regrowth with Micrografts Enriched with Human Follicle Mesenchymal Stem Cells and Platelet-Rich Plasma
January 2022
in “
Springer eBooks
”
autologous not-activated platelet-rich plasma A-PRP micrografts human follicle mesenchymal stem cells HF-MSCs androgenetic alopecia AGA hair thickness hair count hair density Wnt signaling Dermal Papilla Cells platelet-derived growth factors platelet-rich plasma PRP stem cell micrografts mesenchymal stem cells hair loss hair growth
TLDR Using micrografts with stem cells and platelet-rich plasma can safely and effectively help regrow hair.
The study investigated the use of autologous not-activated platelet-rich plasma (A-PRP) and micrografts containing human follicle mesenchymal stem cells (HF-MSCs) as a potential treatment for androgenetic alopecia (AGA). The study involved 35 patients treated with HF-MSCs injections and 57 patients treated with A-PRP. Results showed that 23 weeks after the last A-PRP treatment, there was a mean hair thickness increase of 29 ± 5.0% over baseline values. 12 weeks after the last A-PRP injection, mean hair count and hair density increased by 31 ± 2%. 23 and 44 weeks after the last micrograft injections, patients displayed a hair density improvement of 33% ± 7.5% and 27% ± 3.5%, respectively. The study concluded that HF-MSCs contained in micrografts and A-PRP may represent a safe and effective alternative therapy option against hair loss. The Wnt signaling in Dermal Papilla Cells, signaling from mesenchymal stem cells, and platelet-derived growth factors were identified as key factors that enhance hair growth.
