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330-360 / 1000+ resultsresearch Disturbance of the Circadian System in Shift Work and Its Health Impact
Shift work disrupts the body's natural clock, leading to health problems.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling
Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
![Parallels Between Vertebrate Cardiac and Cutaneous Wound Healing and Regeneration](/images/research/42f109a2-10c5-4e43-bbdb-a21e95131e83/small/12724.jpg)
research Parallels Between Vertebrate Cardiac and Cutaneous Wound Healing and Regeneration
Healing of heart and skin wounds in animals are similar.
research Expression of Vimentin in Hair Follicle Growth Cycle of Inner Mongolian Cashmere Goats
Vimentin is involved in regulating the hair growth cycle in Inner Mongolian Cashmere goats.
research Hairless Plays a Role in Formation of Inner Root Sheath via Regulation of Dlx3 Gene
Hairless protein affects hair follicle structure by regulating the Dlx3 gene.
research Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 NKG2D Lymphocytes in Alopecia Areata Patients
EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
![A Systematic Simulation-Based Meta-Analytical Framework for Prediction of Physiological Biomarkers in Alopecia](/images/research/1ebe35ce-802a-4eb2-acf5-3aee4e3cea80/small/17701.jpg)
research A Systematic Simulation-Based Meta-Analytical Framework for Prediction of Physiological Biomarkers in Alopecia
The study identified 12 potential biomarkers for hair loss and how they affect hair growth.
research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
![Antioxidation, Anti-Inflammation, and Regulation of SRD5A Gene Expression of Oryza Sativa cv. Bue Bang 3 CMU Husk and Bran Extracts as Androgenetic Alopecia Molecular Treatment Substances](/images/research/46acdcf1-d809-420e-a42e-b945da5cc4c8/small/5569.jpg)
research Antioxidation, Anti-Inflammation, and Regulation of SRD5A Gene Expression of Oryza Sativa cv. Bue Bang 3 CMU Husk and Bran Extracts as Androgenetic Alopecia Molecular Treatment Substances
Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.
![A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling](/images/research/8420aa5a-ea08-44b5-9840-bad3d08c5c65/small/19259.jpg)
research A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling
Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.
![A Hairy Situation: PADIs in Regeneration and Alopecia](/images/research/89cd9f85-f570-47a9-8423-0ff142768078/small/19218.jpg)
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
![Effect of Scalp Position on Tensile Properties of Single Hair Fibers](/images/research/0f9f4541-e714-4207-8ca6-0c8dc2340e95/small/23494.jpg)
research Effect of Scalp Position on Tensile Properties of Single Hair Fibers
Hair strength is similar across different scalp areas, and not affected by age, gender, or hair thickness.
![Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells](/images/research/7784f63b-a2b0-445f-a87c-9c3b3aaa843d/small/17318.jpg)
research Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells
Scoparone may help stimulate hair growth by increasing stem cell-related proteins in skin cells.
research Pharmacological Activity Of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research Design and Characterization of Baricitinib Incorporated PLA 3D Printed Pills by Fused Deposition Modeling for Treating Alopecia Areata
The study created 3D-printed pills that effectively release a hair loss treatment drug over 24 hours.
![Selective Sensing of Darolutamide and Thalidomide in Pharmaceutical Preparations and in Spiked Biofluids](/images/research/8e39f5e8-fb66-4d34-afd7-2e2a14610529/small/13068.jpg)
research Selective Sensing of Darolutamide and Thalidomide in Pharmaceutical Preparations and in Spiked Biofluids
A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.
research The Stem Cell Quiescence and Niche Signaling Is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse
Disrupted stem cell signals in hairpoor mice cause hair loss.
research Localized Alopecia and Suppression of Hypothalamic-Pituitary-Adrenal Axis in Dogs Following Treatment with Difluprednate 0.05% Ophthalmic Emulsion
Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.
![Development of the First Health-Related Quality of Life Questionnaires in Arabic for Women with Polycystic Ovary Syndrome: Creation and Reliability Analysis of PCOSQoL-47 and PCOSQoL-42](/images/research/52e35d31-6294-43a2-a4bc-853a6533eecd/small/15838.jpg)
research Development of the First Health-Related Quality of Life Questionnaires in Arabic for Women with Polycystic Ovary Syndrome: Creation and Reliability Analysis of PCOSQoL-47 and PCOSQoL-42
Two new reliable Arabic questionnaires for measuring quality of life in women with PCOS were created, one for married and one for unmarried women.
research Quality of Calcium Food Supplements: Evaluation Compared to Manufacturers' Declarations
Some calcium supplements have more calcium than their labels say, and a few have less.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
![A Large Benign Adrenocortical Adenoma Cosecreting Testosterone and Cortisol](/images/research/d881066e-15a8-46a3-a51b-e1e71aaf1531/small/35453.jpg)
research A Large Benign Adrenocortical Adenoma Cosecreting Testosterone and Cortisol
A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.
research Hydrogel Composites for Multifunctional Biomedical Applications
Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.
![Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study](/images/research/4df7041b-dea0-4e29-8ea9-127869f4069c/small/20565.jpg)
research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
![Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach](/images/research/d613c36b-5b4e-4e0d-aa71-08c368c85adb/small/28668.jpg)
research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
![Genetic Single Nucleotide Polymorphisms of IL-16 and Its Concentration in Patients Infected with Alopecia Areata in Diyala Province, Iraq](/images/research/e26c97b4-48b9-4be5-b1fc-6b863a9a57b0/small/36300.jpg)
research Genetic Single Nucleotide Polymorphisms of IL-16 and Its Concentration in Patients Infected with Alopecia Areata in Diyala Province, Iraq
Certain genetic variations in IL-16 may increase the risk of alopecia areata.
![Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site Distinct from the Legumain-binding Site](/images/research/7922efc4-c285-488f-ae08-7c738a6fa21b/small/35500.jpg)
research Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site Distinct from the Legumain-binding Site
Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
![Careless Talk Costs Lives: Fibroblast Growth Factor Receptor Signalling and the Consequences of Pathway Malfunction](/images/research/b3b76520-e1df-4b8f-ac87-3ad59963e1cc/small/12808.jpg)
research Careless Talk Costs Lives: Fibroblast Growth Factor Receptor Signalling and the Consequences of Pathway Malfunction
Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.