TLDR NIR-II imaging effectively tracked stem cells that helped repair facial nerve defects in rats.
The study investigated the use of second near-infrared (NIR-II) fluorescence imaging to track CelTrac1000-labeled hair follicle epidermal neural crest stem cells (EPI-NCSCs) in repairing rat facial nerve defects. Thirty adult male rats were divided into three groups: ANA + cells, ANA, and autograft. Over 14 weeks, EPI-NCSCs were successfully visualized and shown to survive in the acellular nerve allografts (ANAs). The ANA + cells group exhibited lower recovery metrics compared to the autograft group, which had the best outcomes. The study concluded that NIR-II imaging effectively monitored EPI-NCSCs, which aided in repairing facial nerve defects in rats.
5 citations,
January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
December 2022 in “Stem Cells and Development” Exosomes from stem cells help improve nerve repair in rats.
8 citations,
July 2022 in “BMC neuroscience” Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
11 citations,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
5 citations,
January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
25 citations,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
17 citations,
January 2014 in “Stem Cells Translational Medicine” Canine epidermal neural crest stem cells could be a promising treatment for spinal cord injuries in dogs.
