George Ernest Rogers 1927–2021

June 2023 in “ Historical records of Australian science/Historical Records of Australian Science ”

Richard Rogers

keratins keratinization electron microscopy hair structure wool structure citrulline keratin proteins transglutaminase peptidylarginine deiminase ribosomal-dependent keratin protein synthesis hair keratin protein biosynthesis feather follicle development avian keratin genes wool keratin genes keratin hair protein synthesis feather development bird keratin genes

Studysummary This biographical abstract highlights George Rogers' pioneering contributions to the understanding of keratin molecular structure and keratinisation biochemistry, including the application of electron microscopy to hair ultrastructure and the discovery of enzymes and gene transcription processes relevant to keratin proteins.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on publish.csiro.au →

Discuss this study in the Community →

Research cited in this study

12 / 12 results

research Targeted Expression of SV40 T Antigen in the Hair Follicle of Transgenic Mice Produces an Aberrant Hair Phenotype

14 citations , March 1995 in “Journal of cell science”

This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.

research Cyclic Hair Loss and Regrowth in Transgenic Mice Overexpressing an Intermediate Filament Gene

93 citations , May 1990 in “The EMBO Journal”

Mice with extra sheep genes had hair that fell out and regrew in cycles.

research Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle

116 citations , April 1986 in “The journal of cell biology/The Journal of cell biology”

This study reports that a 190,000 molecular weight protein, identified as trichohyalin, may play a matrix role in the development of inner root sheaths in hair follicles.

research Ribonucleic Acids Coding for the Keratin Complex of Hair

5 citations , January 1981

This article reviews the classification and complexity of keratin protein groups in hair follicles, but reports no new experimental results on their transcriptional events.

research Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles

59 citations , July 1972 in “Biochemistry”

This study investigated the formation of a specific chemical crosslink in hair proteins and explored the role of transamidase enzymes in hair follicles.

research The Occurrence of the ε-(γ-Glutamyl)Lysine Cross-Link in the Medulla of Hair and Quill

49 citations , January 1972 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”

research Iε-(γ-Glutamyl) Lysine Cross-Linkage in Citrulline-Containing Protein Fractions From Hair

125 citations , February 1971 in “Biochemistry”

Specific cross-linkages help make hair proteins stable and strong.

research Newer Findings on the Enzymes and Proteins of Hair Follicles

82 citations , November 1959 in “Annals of the New York Academy of Sciences”

This article reviews recent findings on enzymes and proteins in hair follicles and reports no new experimental results.

research Electron Microscope Studies of Hair and Wool

191 citations , November 1959 in “Annals of the New York Academy of Sciences”

This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.

research Content of Citrulline and Other Amino Acids in Hair Follicle Protein

88 citations , July 1958 in “Nature”

This study reported the first known occurrence of citrulline in an animal protein, specifically in the fibrous protein of hair follicle inner root sheaths.

research Some Observations on the Proteins of the Inner Root Sheath Cells of Hair Follicles

34 citations , July 1958 in “Biochimica et Biophysica Acta”

research Electron Microscope Observations on the Glassy Layer of the Hair Follicle

24 citations , December 1957 in “Experimental Cell Research”

This study observed that the glassy layer of hair follicles in guinea pigs consists of thick collagen-type fibrils organized into two distinct arrays, whereas in young mice, the fibrils are thinner and develop between the outer root sheath and fibroblasts.