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The study created a new method to test drugs that affect hormone processing in skin.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Certain drugs that block specific enzymes can help treat prostate diseases.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

The compound 4c showed strong potential as an anticancer agent.

Glioblastoma cells can make androgens, which might help the tumor grow.

A new method accurately measures nine specific hormones in human blood.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

A new method was developed to make finasteride for treating hair loss.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Muscles can make their own androgens, which may help muscle growth.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Finasteride doesn't affect ovulation in normal women.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Finasteride improved symptoms in a schizophrenia patient.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.