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A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride potentially treats hair loss by reducing DHT production.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Some herbs show promise as antiandrogenic agents.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Finasteride helps treat hair loss by blocking enzyme activity.

Teak leaf extract contains compounds that could help treat hair loss.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Suppressing certain hormones might help prevent prostate cancer.

A plant extract was found to effectively block an enzyme related to male hormone-related diseases.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

Dutasteride is more effective than finasteride for hair loss treatment.

Hibiscus rosa sinensis may help manage hair loss.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Rubus coreanum may help hair growth but not through the tested mechanisms, and none of the herbal extracts help with acne.

Extracts improve hair growth in alopecia.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.